Sequence 1: | NP_001285494.1 | Gene: | tbc / 318059 | FlyBaseID: | FBgn0052506 | Length: | 1155 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_001254500.1 | Gene: | TBC1D2 / 55357 | HGNCID: | 18026 | Length: | 928 | Species: | Homo sapiens |
Alignment Length: | 686 | Identity: | 123/686 - (17%) |
---|---|---|---|
Similarity: | 235/686 - (34%) | Gaps: | 218/686 - (31%) |
- Green bases have known domain annotations that are detailed below.
Fly 587 EGLTKER----------WQLLNVNGVLENATEFYRLVY--FGGVQPELRQEVWPYLLGHYAFGST 639
Fly 640 TEDRKKQDETCKHYYETTMSEWLAVDAIVQQREKEKTARAVAKLSSGSNSGNDRTVRAADLEAGG 704
Fly 705 DLENEVFEDISDISDPGDLEFDEQQQQQQQQAECAVSGNHLTVKPIPR-AMKTSTDSGHVDESFN 768
Fly 769 ELDEPDEED------NKQKQQQDEKISESESKLPDYRKLEEQINQEPSCSASTASSYETVGPGEV 827
Fly 828 HQ-----RPNSDTRSVLSPE--YLSADDLQLPD--------------DEDAVRPPPPPAAAAVII 871
Fly 872 TKASVDITNWERSPKAAEGDQMSPLEE-----------------------QAGESGGAG-VNMDA 912
Fly 913 LQQP-KSACAS-----PASS------------------------------NGGVYSSELLEQFGL 941
Fly 942 NLH----RIEKDVQRCDRNYWYF---ANENLDKLRNVISTYVWEHLDVGYMQGMCDLVAPLLVIF 999
Fly 1000 DDESLSYSCFCKLMERMIENFPSGGAMDMHFANMRSLIQILDSEMYDLMDSNGDYTHF---YFCY 1061
Fly 1062 RWFLLDFKRELVYDDVFATWEVIWAAKHIASGHFVLF-LALALLE-TYRDII-LSNSMDFTDVIK 1123
Fly 1124 FFNEMAERHNAQSVLQLA--------RSLVLQLQMI 1151 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
tbc | NP_001285494.1 | RUN | 45..218 | CDD:280855 | |
PH_RUTBC | 292..466 | CDD:275431 | |||
TBC | 923..1087 | CDD:214540 | 42/203 (21%) | ||
TBC1D2 | NP_001254500.1 | Interaction with CADH1 | 1..169 | ||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..39 | ||||
PH_TBC1D2A | 47..147 | CDD:269966 | |||
PH | 47..139 | CDD:278594 | |||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 225..275 | ||||
Interaction with RAC1. /evidence=ECO:0000269|PubMed:20116244 | 295..433 | 34/198 (17%) | |||
TBC | 625..837 | CDD:214540 | 47/218 (22%) | ||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E1_COG5210 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 0 | 0.000 | Not matched by this tool. | |||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
1 | 0.900 |