DRSC/TRiP Functional Genomics Resources

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Protein Alignment tbc and TBC1D13

DIOPT Version :9

Sequence 1:NP_001285494.1 Gene:tbc / 318059 FlyBaseID:FBgn0052506 Length:1155 Species:Drosophila melanogaster
Sequence 2:NP_060671.3 Gene:TBC1D13 / 54662 HGNCID:25571 Length:400 Species:Homo sapiens


Alignment Length:379 Identity:84/379 - (22%)
Similarity:142/379 - (37%) Gaps:91/379 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly   801 LEEQINQEPSCSASTASSYETVGPGEVHQRPNSDTRSVLSPEYLSADDLQLPDDEDAVRPPPPPA 865
            |.|.|.|.....|:...|.|.|...:....||.|:|   ...|...:::.|..|:|..|..|   
Human    74 LREMIIQPGIAKANMGVSREDVTFEDHPLNPNPDSR---WNTYFKDNEVLLQIDKDVRRLCP--- 132

  Fly   866 AAAVIITKASVDITNWERSP------------------KAAEGDQMSPLEEQAGESGGAGV-NMD 911
                       ||:.::|:.                  |..|   .:.|:.|......:|| || 
Human   133 -----------DISFFQRATDYPCLLILDPQNEFETLRKRVE---QTTLKSQTVARNRSGVTNM- 182

  Fly   912 ALQQPKSACASPASSNGGVYSSELLEQFGLNLHRIEKDVQRCDRNYWYFANENLDKLRNVISTYV 976
                     :||..::  |.||         |:..|.....|:. :|       :.:..::..|.
Human   183 ---------SSPHKNS--VPSS---------LNEYEVLPNGCEA-HW-------EVVERILFIYA 219

  Fly   977 WEHLDVGYMQGMCDLVAPLLVIF----------DDESLSYSCFCKLMERMIENF-----PSGGAM 1026
            ..:..:.|:|||.::|.||...|          ..|:.::.||..||..:.:||     .|...:
Human   220 KLNPGIAYVQGMNEIVGPLYYTFATDPNSEWKEHAEADTFFCFTNLMAEIRDNFIKSLDDSQCGI 284

  Fly  1027 DMHFANMRSLIQILDSEMY-DLMDSNGDYTHFYFCYRWFLLDFKRELVYDDVFATWEVIWAAKHI 1090
            ......:.|.::..|.|:| .|.:.|  ....:|.:||..|...:|.:..||...|:.::|..: 
Human   285 TYKMEKVYSTLKDKDVELYLKLQEQN--IKPQFFAFRWLTLLLSQEFLLPDVIRIWDSLFADDN- 346

  Fly  1091 ASGHFVLFLALALLETYRDIILSNSMDFTDVIKFFNEMAERHNAQSVLQLARSL 1144
             ...|:|.:..|:|...|:.:|..  |||..::...:.......| :||.|:.|
Human   347 -RFDFLLLVCCAMLMLIREQLLEG--DFTVNMRLLQDYPITDVCQ-ILQKAKEL 396

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
tbcNP_001285494.1 RUN 45..218 CDD:280855
PH_RUTBC 292..466 CDD:275431
TBC 923..1087 CDD:214540 39/179 (22%)
TBC1D13NP_060671.3 TBC 32..367 CDD:214540 75/345 (22%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5210
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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