DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tbc and CG8155

DIOPT Version :9

Sequence 1:	NP_001285494.1	Gene:	tbc / 318059	FlyBaseID:	FBgn0052506	Length:	1155	Species:	Drosophila melanogaster
Sequence 2:	NP_611029.3	Gene:	CG8155 / 36698	FlyBaseID:	FBgn0034009	Length:	1098	Species:	Drosophila melanogaster

Alignment Length:	197	Identity:	65/197 - (32%)
Similarity:	99/197 - (50%)	Gaps:	14/197 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   904 GGA-GVNMDALQ-------QPKSACASPASSNGGVYSSELLEQFGLNLHRIEKDVQRCDRNYWYF 960
            ||| |:.:|..|       :.:..|....:....|....:..:.......::|||.|.||.:.::
  Fly   245 GGANGLALDGHQRMEFMRRKSEQYCRLRDTWKAAVKRGSVAGELAYVTSMVKKDVLRTDRLHPFY 309

  Fly   961 A----NENLDKLRNVISTYVWEHLDVGYMQGMCDLVAPLLVIFDDESLSYSCFCKLMERMIENFP 1021
            |    |:|:..|.|:::||...|..|.|.|||.|:.:||||..:||:.:|.|||.:|.||..||.
  Fly   310 AGSDDNQNIAALFNILTTYALNHPSVSYCQGMSDIASPLLVTMNDEAQAYICFCAIMSRMRGNFM 374

  Fly  1022 SGG-AMDMHFANMRSLIQILDSEMYDLMDSNGDYTHFYFCYRWFLLDFKRELVYDDVFATWEVIW 1085
            ..| ||...||::...:...|.|.::.:.|. ......|||||.||:.|||..::|.....||.|
  Fly   375 LDGIAMTQKFAHLTEALSFYDPEFWEYLKSQ-QADDLLFCYRWLLLELKREFPFEDALRMLEVQW 438

  Fly  1086 AA 1087
            ::
  Fly   439 SS 440

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tbc	NP_001285494.1	RUN	45..218	CDD:280855
		PH_RUTBC	292..466	CDD:275431
		TBC	923..1087	CDD:214540	58/168 (35%)
CG8155	NP_611029.3	TBC	225..439	CDD:214540	64/194 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45456617
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR22957
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.930