Protein Alignment tbc and Tbc1d10b

DIOPT Version :9

• Sequence 1: NP_001285494.1
• Gene: tbc / 318059
• FlyBaseID: FBgn0052506
• Length: 1155
• Species: Drosophila melanogaster
• Sequence 2: NP_001102391.1
• Gene: Tbc1d10b / 365372
• RGDID: 1309191
• Length: 795
• Species: Rattus norvegicus
• Alignment Length: 523
• Identity: 97/523 - (18%)
• Similarity: 157/523 - (30%)
• Gaps: 181/523 - (34%)

  Fly   720 PGDLEFDEQQQQQQQQAECAVSGN--HLTVKPIPRAMKTSTDSGHVDESFNE--------LDEPD 774
            ||.|       |.........:|:  .||::..|.|.||........|:..|        .|.|.
  Rat    64 PGSL-------QTSASTPTTATGSTVELTLEASPEAAKTQEFPAPAAEAGAETSVALVLGTDTPK 121

  Fly   775 EEDNKQKQQQDEKISESESKLPDYRKLEEQINQEPSCS---ASTASSYETV--GPGEVHQRPNSD 834
            .|:.:......   ..:.::.|. |.....:..:|..:   .:|.:|..|.  |.|:|.....:.
  Rat   122 TEEARASPVPG---PGTPTRTPS-RTASGALTAKPPLAPKPGTTVASGVTARGGAGQVAGGHGAA 182

  Fly   835 TRSVLSPEYLSADDLQLPDDEDAVRPPPP------PAAAAVIITKASVDITNWE----------- 882
            |.:...|         :|:|.......||      ...|.|.:|.|.....|::
  Rat   183 TSASAGP---------VPEDPSGPVTGPPGTCEASAPVARVTVTPAPETTENFQDLGSTSSLGPG 238

  Fly   883 -RSPKAAEGDQMSPLEEQAGESGGAGVNMDALQQPKSACASPASSNG------------------ 928
             ..|:....|.:|.|:..:..||    .:::|....|:..|.:..||
  Rat   239 ISGPRGQAPDTLSYLDSVSLMSG----TLESLTDDVSSVGSDSEINGLALRKTDKYGFLGGSQYS 299

  Fly   929 -------------------------------------------GVYSS-------------ELLE 937
                                                       |:.||             ||||
  Rat   300 GSLESSIPVDVARQRELKWLEMFSNWDKWLSRRFQKVKLRCRKGIPSSLRAKAWQYLSNSKELLE 364

  Fly   938 QFGLN----------------LHRIEKDVQRCDRNYWYFA---NENLDKLRNVISTYVWEHLDVG 983
            |   |                |..||||:.|....:..||   ......|..::..|.....|.|
  Rat   365 Q---NPGKFEELERAPGDPKWLDVIEKDLHRQFPFHEMFAARGGHGQQDLYRILKAYTIYRPDEG 426

  Fly   984 YMQGMCDLVAPLLVIFDDESLSYSCFCKLMERMIENFPSGGAMDMHFANMRSLIQILDSEM-YDL 1047
            |.|....:.|.||:....|. ::.|..::.::.:..:.|.|.         ..|| ||.|: :.|
  Rat   427 YCQAQAPVAAVLLMHMPAEQ-AFWCLVQICDKYLPGYYSAGL---------EAIQ-LDGEIFFAL 480

  Fly  1048 MDSNGDYTHFY----------FCYRWFLLDFKRELVYDDVFATWEVIWAAKHIASGHFVLF-LAL 1101
            :.......|.:          :...||:..|.|.|.:..|...|::.:     ..|..::| :||
  Rat   481 LRRASPLAHRHLRRQRIDPVLYMTEWFMCIFARTLPWASVLRVWDMFF-----CEGVKIIFRVAL 540

  Fly  1102 ALL 1104
            .||
  Rat   541 VLL 543

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tbc	NP_001285494.1	RUN	45..218	CDD:280855
		PH_RUTBC	292..466	CDD:275431
		TBC	923..1087	CDD:214540	46/267 (17%)
Tbc1d10b	NP_001102391.1	TBC	340..545	CDD:214540	50/223 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900