Protein Alignment tbc and Tbc1d10c

DIOPT Version :10

• Sequence 1: NP_608395.6
• Gene: tbc / 318059
• FlyBaseID: FBgn0052506
• Length: 1155
• Species: Drosophila melanogaster
• Sequence 2: NP_001075449.1
• Gene: Tbc1d10c / 361697
• RGDID: 1311490
• Length: 446
• Species: Rattus norvegicus
• Alignment Length: 264
• Identity: 56/264 - (21%)
• Similarity: 90/264 - (34%)
• Gaps: 62/264 - (23%)

  Fly   926 SNGGVYSS--------ELLEQFGLNLHRIEKDVQRCDRNYWYFANENL---------DKLRNVIS 973
            :|.|.|..        :.:|..|.:|||             .|....:         ..|..|:.
  Rat   114 NNPGTYQELAVAPGDPQWMETIGRDLHR-------------QFPLHEMFVSPQGHGQQGLLQVLK 165

  Fly   974 TYVWEHLDVGYMQGMCDLVAPLLVIFDDESLSYSCFCKLMERMIENF--PSGGAMDMHFANMRSL 1036
            .|.....:.||.|....:.|.||:....|. ::.|..::.|..:..:  |...|:.:......:|
  Rat   166 AYTLYRPEQGYCQAQGPVAAVLLMHLPPEE-AFWCLVQICEVYLPGYYGPHMEAVQLDAEVFMAL 229

  Fly  1037 IQILDSEMYDLMDSNGDYTHFYFCYRWFLLDFKRELVYDDVFATWEVIWAAKHIASGHFVLF--- 1098
            ::.|...:|..:...|.....|. ..|||..|.|.|.:..|...|:..     ::.|..|||
  Rat   230 LRRLLPRVYKHLQQVGVGPLLYL-PEWFLCLFTRSLPFPIVLRIWDAF-----LSEGAKVLFRAG 288

  Fly  1099 -----LAL----------ALLETYRDIILSNSMDFTDVIKFFNEMAERHN-AQSVLQLARSLVLQ 1147
                 |||          .||||...:.........:.:    .|::.|| |.|...|.|.:.:|
  Rat   289 LTLMRLALGTVEQRTACPGLLETLGALRTIPPTQLQEEV----FMSQVHNVALSERDLQREIRIQ 349

  Fly  1148 LQMI 1151
            |..:
  Rat   350 LAQL 353

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tbc	NP_608395.6	RUN_SGSM1_like	21..214	CDD:439049
		PH_RUTBC	292..466	CDD:275431
		TBC	923..1087	CDD:214540	36/179 (20%)
Tbc1d10c	NP_001075449.1	TBC	89..294	CDD:214540	40/199 (20%)