Protein Alignment tbc and tbc-12

DIOPT Version :9

• Sequence 1: NP_001285494.1
• Gene: tbc / 318059
• FlyBaseID: FBgn0052506
• Length: 1155
• Species: Drosophila melanogaster
• Sequence 2: NP_508458.1
• Gene: tbc-12 / 180556
• WormBaseID: WBGene00044061
• Length: 614
• Species: Caenorhabditis elegans
• Alignment Length: 438
• Identity: 84/438 - (19%)
• Similarity: 153/438 - (34%)
• Gaps: 112/438 - (25%)

  Fly   731 QQQQQAECAVSGNHLTVKPIPRAMKTSTDSGHVDESFNELDEPDEEDNKQKQQQDEKISESESKL 795
            :.:|....|.:|..|..:|.....|::.::.|..:.:.::    .|..|:|:|:.||  |.....
 Worm   199 RNKQSGVMATTGLILEERPSGLPSKSADEAAHHKQMYLDI----LEQAKKKEQRAEK--ERLQAK 257

  Fly   796 PDYRKLEEQINQEPSCSASTASSYETVGPGEVHQRPNSDTRSVLSPEYLSADDLQLPDDEDAVRP 860
            .:.::||||      .:|......|.:.|.....:.:...|.:.
 Worm   258 AEQKRLEEQ------TAAHCRVWVEQILPKWEEMKDSKRCRELW--------------------- 295

  Fly   861 PPPPAAAAVIITKASVDITNWERSPKAAEG---------------DQMSPLEEQAGESGGAGVNM 910
                                |:..|....|               :....|.:||.|.    :..
 Worm   296 --------------------WQGVPAKVRGELWFLTIGNQIEITKELYDGLMDQAEEK----IAK 336

  Fly   911 DALQQPKSACASPASSNGGVYSSELLEQFGLNLHRIEKDVQRCDRNYWYFANEN--LDKLRNVIS 973
            ...:|.|::.                |:...::.:|..|..|...:...|..:.  .|.|..::|
 Worm   337 QLAEQNKNSA----------------ERKETSVTQIHLDATRTFTSLGMFQKDGPYYDHLLKLLS 385

  Fly   974 TYVWEHLDVGYMQGMCDLVAPLLVIFDDESLSYSCFCKLMERMIENFPSG---GAMDMHF-ANMR 1034
            .|.....|:||:|.|..:.|.||:..|... ::..|..|::|.:::...|   ..|..:| |..|
 Worm   386 AYAILRPDIGYVQSMTFIAAVLLIQMDPYP-AFISFANLLDRSLQSAFFGLKQPQMTEYFIAYDR 449

  Fly  1035 SLIQILDS--EMYDLMDSNGDYTHFYFCYRWFLLDFKRELVYDDVFATWEVIWAAKHIASGHFVL 1097
            .|.|.|.:  :..|.:|...|    .:...|....:.:.|..|.....|:|     :...|...|
 Worm   450 YLEQELPALHQHLDKLDVRPD----LYLIEWTFAMYAKSLPLDVTCRIWDV-----YFRDGEEFL 505

  Fly  1098 F-LALALLETYRDIILSNSMDFTDVIKFFNEMAERHNAQSVLQLARSL 1144
            | .||.:|..|...:|  :|||.|.::|..::.   |..:..:|.|::
 Worm   506 FKAALGILRMYEPKLL--TMDFDDCVEFLTKLP---NTLTGAELFRNI 548

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tbc	NP_001285494.1	RUN	45..218	CDD:280855
		PH_RUTBC	292..466	CDD:275431
		TBC	923..1087	CDD:214540	37/171 (22%)
tbc-12	NP_508458.1	TBC	295..521	CDD:214540	53/296 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810