DRSC/TRiP Functional Genomics Resources

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Protein Alignment tbc and TBC1D21

DIOPT Version :9

Sequence 1:NP_001285494.1 Gene:tbc / 318059 FlyBaseID:FBgn0052506 Length:1155 Species:Drosophila melanogaster
Sequence 2:XP_006720472.1 Gene:TBC1D21 / 161514 HGNCID:28536 Length:399 Species:Homo sapiens


Alignment Length:221 Identity:54/221 - (24%)
Similarity:93/221 - (42%) Gaps:47/221 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly   935 LLEQFGLNLHR--------IEKDVQRC-DRNYWYFANENLDKLR---NVISTYVWEHLDVGYMQG 987
            |||    ||||        |.:|:|:. |::  ...|..:||.|   .::.:||. :....|.||
Human   107 LLE----NLHRNFTETRNNIARDIQKIYDKD--PLGNVLIDKKRLEKILLLSYVC-NTQAEYQQG 164

  Fly   988 MCDLVA--PLLVIFDDESL----------SYSCFCKLMERMIENFPSGGAMDMHFANMRSLIQIL 1040
            ..:::.  .|:|..|.|:.          .:||        :.|......:||    :.:||..|
Human   165 FHEMMMLFQLMVEHDHETFWLFQFFLQKTEHSC--------VINIGVAKNLDM----LSTLITFL 217

  Fly  1041 DSEMYDLMDSNGDYTHFYFCYRWFLLDFKREL-VYDDVFATWEVIWAAKHIASGHFVLFLALALL 1104
            |....:.:...|... ....:.||...|:|.. .:|||:..|||:...|  ...:|.:.:|.::|
Human   218 DPVFAEHLKGKGAGA-VQSLFPWFCFCFQRAFKSFDDVWRLWEVLLTGK--PCRNFQVLVAYSML 279

  Fly  1105 ETYRDIILSNSMDFTDVIKFFNEMAE 1130
            :..|:.:|..||...|::...|.:.:
Human   280 QMVREQVLQESMGGDDILLACNNLID 305

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
tbcNP_001285494.1 RUN 45..218 CDD:280855
PH_RUTBC 292..466 CDD:275431
TBC 923..1087 CDD:214540 44/176 (25%)
TBC1D21XP_006720472.1 TBC 62..287 CDD:214540 49/201 (24%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5210
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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