DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32483 and Cpvl

DIOPT Version :9

Sequence 1:	NP_728540.1	Gene:	CG32483 / 318050	FlyBaseID:	FBgn0052483	Length:	439	Species:	Drosophila melanogaster
Sequence 2:	XP_006506676.1	Gene:	Cpvl / 71287	MGIID:	1918537	Length:	484	Species:	Mus musculus

Alignment Length:	447	Identity:	113/447 - (25%)
Similarity:	195/447 - (43%)	Gaps:	83/447 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 PGEQD---WGYVDVRP--GAHMFYWLYYTTANVSSYTERPLAIWLQGGPGASSTGYGNFEELGPV 83
            ||..|   .||:.|..  .:::|:|.:.......   :.|:.:|||||||.||. :|.|.|.||.
Mouse    75 PGMNDKSYAGYITVNQTYNSNLFFWFFPARMQPE---DAPVVLWLQGGPGGSSM-FGLFVEHGPY 135

  Fly    84 DLYGDW----RSWTWVKDMNVLFIDNPVGSGFSYVDNTAFYTATNKEIALDLVELMKGFYTLHPE 144
            .:..:.    |.:.|...:::|:||||||:|||:.|:...|..:..::|.||...:..|:||.||
Mouse   136 IITSNMTVVARDFPWTFTLSMLYIDNPVGTGFSFTDHFQGYATSEDDVAQDLYSALIQFFTLFPE 200

  Fly   145 FEEVPLHIFCESYGGKMAPEFALELYYAKKRGEVKSNLTSVALGDPWTSPIDSVLAWGPFLREMG 209
            :.:...::..|||.||..|..|..::......:.|..|..:|:||.:|.|...:..:..||.|:|
Mouse   201 YAKNDFYVTGESYAGKYVPALAHYIHSLNPVRKFKIRLKGIAIGDAYTDPESIIGGYAAFLYEIG 265

  Fly   210 IVDHAGYNAIQEAANFTAQLVEEERWIQATYQWGNTQWEVM-KASKG---------------VDF 258
            ::|.......|:..:...:.::|:.|::|        :|:: |...|               .::
Mouse   266 LLDEQQQKYFQKQCSKCVKYIKEQEWMKA--------FEILDKLLDGDVTTGSSFFQNVTGCTNY 322

  Fly   259 YNVLKETKGGLYQRSKALTSEERLYRTMVKYDIDEDRTKLLEDLMRGPVAETLGIP---SNVIWG 320
            ||:|:.|:           .:|:.|                       .|:.|.:|   ..:..|
Mouse   323 YNILQCTE-----------PKEQSY-----------------------FAKFLTLPQVRQAIHVG 353

  Fly   321 SQS---GTTFDIH-RTDFMKPVIHIVNELLEKTPLKVGVFSGGLDLICATPGTVNWIAKLDWSRK 381
            :|:   |...:.| |.|.:|.|...::|::..  .||.:::|.||:|.|...|...:..:||...
Mouse   354 NQNFSDGAEVEKHLREDTVKSVKPWLSEIMNY--YKVLIYNGQLDIIVAAALTERSLMAMDWKGS 416

  Fly   382 DEYLAAPRNGITV---DRILEGYQKTGGNFTMFWINRSGHMAPADNPAAMSHVLREF 435
            ..|..|.|....:   |..:.||.:..|.|....:...||:.|.|.|.....::..|
Mouse   417 RAYRRARRKVWKIFKSDNEVAGYVRRVGKFHQVIVRGGGHILPYDQPMRSFDMINRF 473

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32483	NP_728540.1	Peptidase_S10	18..437	CDD:298660	113/447 (25%)
Cpvl	XP_006506676.1	Peptidase_S10	78..474	CDD:366108	111/444 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2939
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54069
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R172
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.850