Protein Alignment CG32483 and CTSA

DIOPT Version :10

• Sequence 1: NP_728540.1
• Gene: CG32483 / 318050
• FlyBaseID: FBgn0052483
• Length: 439
• Species: Drosophila melanogaster
• Sequence 2: NP_000299.3
• Gene: CTSA / 5476
• HGNCID: 9251
• Length: 480
• Species: Homo sapiens
• Alignment Length: 501
• Identity: 115/501 - (22%)
• Similarity: 196/501 - (39%)
• Gaps: 111/501 - (22%)

  Fly     5 LVALLALFAALAHGKPGYG-----PG-------EQDWGYVDVRPGAHMFYWLYYTTANVSSYTER 57
            |:.||..:|:.....|...     ||       .|..||:......|:.||...:..:..:   .
Human    15 LLLLLVSWASRGEAAPDQDEIQRLPGLAKQPSFRQYSGYLKGSGSKHLHYWFVESQKDPEN---S 76

  Fly    58 PLAIWLQGGPGASSTGYGNFEELGPVDLYGD-----WRSWTWVKDMNVLFIDNPVGSGFSYVDNT 117
            |:.:||.||||.||.. |...|.||..:..|     :..::|....|||::::|.|.||||.|:
Human    77 PVVLWLNGGPGCSSLD-GLLTEHGPFLVQPDGVTLEYNPYSWNLIANVLYLESPAGVGFSYSDD- 139

  Fly   118 AFYTATNKEIALDLVELMKGFYTLHPEFEEVPLHIFCESYGGKMAPEFALELYYAKKRGEVKSNL 182
            .||...:.|:|....|.::.|:.|.||::...|.:..|||.|...|..|:.:..     :...||
Human   140 KFYATNDTEVAQSNFEALQDFFRLFPEYKNNKLFLTGESYAGIYIPTLAVLVMQ-----DPSMNL 199

  Fly   183 TSVALGDPWTS--PIDSVLAWGPFLREMGIVDHAGYNAI------QEAANF--------TAQLVE 231
            ..:|:|:..:|  ..|:.|.:  |....|::.:..::::      |...||        ...|.|
Human   200 QGLAVGNGLSSYEQNDNSLVY--FAYYHGLLGNRLWSSLQTHCCSQNKCNFYDNKDLECVTNLQE 262

  Fly   232 EERWIQATYQWGNTQWEVMKASKGVDFYNVLKETKGGL-----YQRSKALTSE------------ 279
            ..|.:      ||:         |::.||:.....||:     |::...:..:
Human   263 VARIV------GNS---------GLNIYNLYAPCAGGVPSHFRYEKDTVVVQDLGNIFTRLPLKR 312

  Fly   280 ---ERLYRT--MVKYDIDEDRTKLLEDLMRGP-VAETLGIPS--------NVIWGSQSGTTFDIH 330
               :.|.|:  .|:.|.....|......:..| |.:.|.||.        |.:...|....:...
Human   313 MWHQALLRSGDKVRMDPPCTNTTAASTYLNNPYVRKALNIPEQLPQWDMCNFLVNLQYRRLYRSM 377

  Fly   331 RTDFMKPVIHIVNELLEKTPLKVGVFSGGLDLICATPGTVNWIAKLDWSRKDEYLAAP---RNGI 392
            .:.::|        ||.....::.:::|.:|:.|...|...::..|  ::|.|....|   :.|.
Human   378 NSQYLK--------LLSSQKYQILLYNGDVDMACNFMGDEWFVDSL--NQKMEVQRRPWLVKYGD 432

  Fly   393 TVDRILEGYQKTGGNFTMFWINRSGHMAPADNPAAMSHVLREFTSF 438
            :.::| .|:.|...:.....|..:|||.|.|.|      |..||.|
Human   433 SGEQI-AGFVKEFSHIAFLTIKGAGHMVPTDKP------LAAFTMF 471

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32483	NP_728540.1	Peptidase_S10	18..437	CDD:459815	109/485 (22%)
CTSA	NP_000299.3	Peptidase_S10	39..476	CDD:459815	110/477 (23%)