DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32483 and scpep1

DIOPT Version :9

Sequence 1:	NP_728540.1	Gene:	CG32483 / 318050	FlyBaseID:	FBgn0052483	Length:	439	Species:	Drosophila melanogaster
Sequence 2:	NP_956486.1	Gene:	scpep1 / 393161	ZFINID:	ZDB-GENE-040426-890	Length:	445	Species:	Danio rerio

Alignment Length:	412	Identity:	167/412 - (40%)
Similarity:	239/412 - (58%)	Gaps:	15/412 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 EQDWGYVDVRPGAHMFYWLYYTTANVSSYTERPLAIWLQGGPGASSTGYGNFEELGPVDLYGDWR 90
            ::.|||||||.|||||:||||..::.:||.|.||.:|||||||.||.|:|||||:||:|.....|
Zfish    30 KESWGYVDVRDGAHMFWWLYYANSSSASYKELPLVMWLQGGPGGSSCGFGNFEEIGPLDRDLKLR 94

  Fly    91 SWTWVKDMNVLFIDNPVGSGFSYVDNTAFYTATNKEIALDLVELMKGFYTLHPEFEEVPLHIFCE 155
            ..:||:..:|||:|||||:|:||.|.....|.....:|.|::.|:|.|::|..||:.:|.:||.|
Zfish    95 ETSWVRAASVLFVDNPVGTGYSYTDTEDALTKDVAMVASDMMVLLKKFFSLKTEFQSIPFYIFSE 159

  Fly   156 SYGGKMAPEFALELYYAKKRGEVKSNLTSVALGDPWTSPIDSVLAWGPFLREMGIVDHAGYNAIQ 220
            |||||||...:|||..|.:.|.:|.|...|||||.|.||||||:.||.:|....::|..|.|.:.
Zfish   160 SYGGKMAAAISLELTKAIQAGSIKCNFAGVALGDSWISPIDSVMTWGAYLYSTSLLDDTGLNEVY 224

  Fly   221 EAANFTAQLVEEERWIQATYQWGNTQWEVMKASKGVDFYNVLKETKGGLYQRSKALTSEERLYRT 285
            .||....:.|::..:::||..|...:..|.:.:.||:|||:|.:....:. :|.|..:.:.....
Zfish   225 TAAKAVMEAVQQGDYLKATDLWSMIENVVEQNTNGVNFYNILTQNSDEMV-KSSADQAADGFLLA 288

  Fly   286 MVKYDIDEDRTKLLEDLMRGPVAETLG-IPSNVIWGSQSGTTFDIHRTDFMKPVIHIVNELLEKT 349
            :.:..|.....:.|.:||.||:.:.|| ||.||.||.|:...|.....||||||:.:|::|| ..
Zfish   289 LKRRHIRPLHRQSLSELMNGPIRQKLGVIPKNVTWGGQAEDVFVSMAGDFMKPVVDVVDQLL-AA 352

  Fly   350 PLKVGVFSGGLDLICATPGTVNWIAKLDWSRKDEY-------LAAPRNGITVDRILEGYQKTGGN 407
            .:.|.|::|.||||..|.|...|:.||.|.....:       |..|:......    .:.||..|
Zfish   353 GVNVTVYNGQLDLIVDTMGQEMWVKKLKWDGLQNFNKLKWTALEDPQEQSQTG----AFYKTYKN 413

  Fly   408 FTMFWINRSGHMAPAD-NPAAM 428
            |..:||.::|||.|:| .|.|:
Zfish   414 FAFYWILKAGHMIPSDQGPMAL 435

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32483	NP_728540.1	Peptidase_S10	18..437	CDD:298660	167/412 (41%)
scpep1	NP_956486.1	Peptidase_S10	26..439	CDD:298660	167/412 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592600
Domainoid	1	1.000	316	1.000	Domainoid score	I1245
eggNOG	1	0.900	-	-		E1_COG2939
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H41443
Inparanoid	1	1.050	317	1.000	Inparanoid score	I2521
OMA	1	1.010	-	-		QHG54069
OrthoDB	1	1.010	-	-		D274674at33208
OrthoFinder	1	1.000	-	-		FOG0003531
OrthoInspector	1	1.000	-	-		otm26594
orthoMCL	1	0.900	-	-		OOG6_105329
Panther	1	1.100	-	-	LDO	PTHR11802
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2409
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.770