DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG32483 and cpy1

DIOPT Version :9

Sequence 1:	NP_728540.1	Gene:	CG32483 / 318050	FlyBaseID:	FBgn0052483	Length:	439	Species:	Drosophila melanogaster
Sequence 2:	NP_594425.1	Gene:	cpy1 / 2542465	PomBaseID:	SPAC19G12.10c	Length:	1002	Species:	Schizosaccharomyces pombe

Alignment Length:	460	Identity:	116/460 - (25%)
Similarity:	184/460 - (40%)	Gaps:	84/460 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 KP---GYGPGEQDWGYVDVRPGAHMFYWLYYTTANVSSYTERPLAIWLQGGPGASSTGYGNFEEL 80
            ||   |....:|..||:||....|:|:|.:.:..:..:   .|:.:||.||||.||. .|.|.||
pombe   577 KPESLGIDTVKQYTGYLDVEDDRHLFFWFFESRNDPEN---DPVVLWLNGGPGCSSL-TGLFMEL 637

  Fly    81 GPVD-----LYGDWRSWTWVKDMNVLFIDNPVGSGFSYVDNTAFYTATNKEIALDLVELMKGFYT 140
            ||..     |..::...:|..:.:|:|:|.|:.:|||..|::...|.|   ...|:...:..|:.
pombe   638 GPSSINIETLKPEYNPHSWNSNASVIFLDQPINTGFSNGDDSVLDTVT---AGKDVYAFLNLFFA 699

  Fly   141 LHPEFEEVPLHIFCESYGGKMAPEFALEL--------YYAKKRGEVKS---NLTSVALGDPWTSP 194
            ..|::..:..||..|||.|...|:||.|:        ::.....|::.   ||.||.:|:..|.|
pombe   700 KFPQYAHLDFHIAGESYAGHYIPQFAKEIMEHNQGANFFVASGYEMEKQYINLKSVLIGNGLTDP 764

  Fly   195 IDSVLAWGPFLREMGIVDHAGYNAI---QEAANFTAQLVEEERWIQATYQWGNTQWEVMKASKGV 256
            :.....:|....|      :.|..|   :|....|.......:.|...||.|.|     ....|.
pombe   765 LVQYYFYGKMACE------SPYGPIMSQEECDRITGAYDTCAKLITGCYQTGFT-----PVCIGA 818

  Fly   257 DFY--NVL--KETKGGLYQRSKALTSEERLYRTMVKYDIDED----------RTKLLEDLMRGP- 306
            ..|  |.:  ..||.||.                 .|||.|:          .|..:|..:...
pombe   819 SLYCNNAMIGPFTKTGLN-----------------IYDIREECRDQEHLCYPETGAIESYLNQEF 866

  Fly   307 VAETLGIPSNVIWGSQSGTTFDIH-----RTDFMKPVIH-IVNELLEKTPLKVGVFSGGLDLICA 365
            |.|.||:..:     ..|...:::     :.|:|:.... .|..:|| ..|.|.:::|..|.||.
pombe   867 VQEALGVEYD-----YKGCNTEVNIGFLFKGDWMRKTFRDDVTAILE-AGLPVLIYAGDADYICN 925

  Fly   366 TPGTVNWIAKLDWSRKDEYLAAPRNGITVDRILEGYQKTGGNFTMFWINRSGHMAPADNPAAMSH 430
            ..|...|...|:|:.:.|:..|.....:.:....|..|:..||....:..:|||.|.:.|.|...
pombe   926 YMGNEAWTDALEWAGQREFYEAELKPWSPNGKEAGRGKSFKNFGYLRLYEAGHMVPFNQPEASLE 990

  Fly   431 VLREF 435
            :|..:
pombe   991 MLNSW 995

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32483	NP_728540.1	Peptidase_S10	18..437	CDD:298660	116/460 (25%)
cpy1	NP_594425.1	DUF4779	344..>419	CDD:292628
		Kex1	540..998	CDD:225490	116/460 (25%)
		Peptidase_S10	578..998	CDD:278857	115/459 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2939
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9280
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R172
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.840