DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG32483 and Scpep1

DIOPT Version :9

Sequence 1:	NP_728540.1	Gene:	CG32483 / 318050	FlyBaseID:	FBgn0052483	Length:	439	Species:	Drosophila melanogaster
Sequence 2:	XP_017452440.1	Gene:	Scpep1 / 114861	RGDID:	620067	Length:	461	Species:	Rattus norvegicus

Alignment Length:	408	Identity:	165/408 - (40%)
Similarity:	239/408 - (58%)	Gaps:	16/408 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 GEQDWGYVDVRPGAHMFYWLYYTTANVSSYTERPLAIWLQGGPGASSTGYGNFEELGPVDLYGDW 89
            |::.|.||.||..|.||:||||.|....:::|.||.:|||||||.||||:|||||:||:|.....
  Rat    45 GKEVWDYVTVREDARMFWWLYYATNPCKNFSELPLVMWLQGGPGGSSTGFGNFEEIGPLDTRLKP 109

  Fly    90 RSWTWVKDMNVLFIDNPVGSGFSYVDNTAFYTATNKEIALDLVELMKGFYTLHPEFEEVPLHIFC 154
            |:.||::..::||:|||||:|||||:.|..|......:|.|::.|:|.|:..|.||:.||.:||.
  Rat   110 RNTTWLQWASLLFVDNPVGTGFSYVNTTDAYAKDLDTVASDMMVLLKSFFDCHKEFQTVPFYIFS 174

  Fly   155 ESYGGKMAPEFALELYYAKKRGEVKSNLTSVALGDPWTSPIDSVLAWGPFLREMGIVDHAGYNAI 219
            ||||||||...:|||:.|.::|.:|.|.:.|||||.|.||:||||:|||:|..:.::|:.|...:
  Rat   175 ESYGGKMAAGISLELHKAIQQGTIKCNFSGVALGDSWISPVDSVLSWGPYLYSVSLLDNKGLAEV 239

  Fly   220 QEAANFTAQLVEEERWIQATYQWGNTQWEVMKASKGVDFYNVLKETKGGLYQRSKALTSEERLYR 284
            .:.|......|.:..:.:||..||..:..:.|.:.||:|||:|.::.......|........|.|
  Rat   240 SDIAEQVLNAVNKGFYKEATQLWGKAEMIIEKNTDGVNFYNILTKSTPDTSMESSLEFFRSPLVR 304

  Fly   285 TMVKYDIDEDRTKLLEDLMRGPVAETLG-IPSNVIWGSQSGTTFDIHRTDFMKPVIHIVNELLEK 348
            ...:: :...:...|..||.||:.:.|. ||.:|.||:||.:.|.....|||||||.||:.|||
  Rat   305 LCQRH-VRHLQGDALSQLMNGPIKKKLKIIPDDVSWGAQSSSVFISMEEDFMKPVIDIVDTLLE- 367

  Fly   349 TPLKVGVFSGGLDLICATPGTVNWIAKLDWSRKDEY--------LAAPRNGITVDRILEGYQKTG 405
            ..:.|.|::|.||||..|.|..:|:.||.|.:...:        ...|::..|     ..:.|:.
  Rat   368 LGVNVTVYNGQLDLIVDTIGQESWVQKLKWPQLSRFNQLKWKALYTNPKSSET-----SAFVKSY 427

  Fly   406 GNFTMFWINRSGHMAPAD 423
            .|...:||.::|||.|||
  Rat   428 ENLAFYWILKAGHMVPAD 445

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32483	NP_728540.1	Peptidase_S10	18..437	CDD:298660	165/408 (40%)
Scpep1	XP_017452440.1	Peptidase_S10	46..455	CDD:395361	164/407 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166350914
Domainoid	1	1.000	312	1.000	Domainoid score	I1263
eggNOG	1	0.900	-	-		E1_COG2939
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H41443
Inparanoid	1	1.050	312	1.000	Inparanoid score	I2504
OMA	1	1.010	-	-		QHG54069
OrthoDB	1	1.010	-	-		D274674at33208
OrthoFinder	1	1.000	-	-		FOG0003531
OrthoInspector	1	1.000	-	-		otm44704
orthoMCL	1	0.900	-	-		OOG6_105329
Panther	1	1.100	-	-	LDO	PTHR11802
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2409
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770