DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ppt1 and PPT1

DIOPT Version :9

Sequence 1:	NP_001285024.1	Gene:	Ppt1 / 31805	FlyBaseID:	FBgn0030057	Length:	314	Species:	Drosophila melanogaster
Sequence 2:	NP_000301.1	Gene:	PPT1 / 5538	HGNCID:	9325	Length:	306	Species:	Homo sapiens

Alignment Length:	276	Identity:	153/276 - (55%)
Similarity:	200/276 - (72%)	Gaps:	2/276 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 PEVLPVVLWHGMGDTCCVPFSLGAIMNLIVEQTKGGYVRSLQIGGNVLIDWQSGFFIHPNEQVDY 102
            |..||:|:||||||:||.|.|:|||..::.::..|.||.||:||..::.|.::.||::.|.||..
Human    30 PAPLPLVIWHGMGDSCCNPLSMGAIKKMVEKKIPGIYVLSLEIGKTLMEDVENSFFLNVNSQVTT 94

  Fly   103 VCKQLLQDEHLAKGYHAIGFSQGGQFLRAVAERCPNPPMRNLITLGGQHQGIFGLPMCPTLTEKP 167
            ||:.|.:|..|.:||:|:|||||||||||||:|||:|||.|||::||||||:||||.||..:...
Human    95 VCQALAKDPKLQQGYNAMGFSQGGQFLRAVAQRCPSPPMINLISVGGQHQGVFGLPRCPGESSHI 159

  Fly   168 CDYITRLLDNAAYAPEVQKALVQATYWHDPIMENKYRLGSTFLADINNELFINKFYIENLQKLKK 232
            ||:|.:.|:..||:..||:.||||.||||||.|:.||..|.||||||.|..||:.|.:||..|||
Human   160 CDFIRKTLNAGAYSKVVQERLVQAEYWHDPIKEDVYRNHSIFLADINQERGINESYKKNLMALKK 224

  Fly   233 FVMVQFLNDTIVQPKESQWFQYYTTGQNKVIQPFTESKVY-QD-LGLDKMHRQGQLVFLGVEGDH 295
            ||||:||||:||.|.:|:||.:|.:||.|...|..|:.:| || |||.:|...||||||..||||
Human   225 FVMVKFLNDSIVDPVDSEWFGFYRSGQAKETIPLQETSLYTQDRLGLKEMDNAGQLVFLATEGDH 289

  Fly   296 LAISKAWFIQNIVPLL 311
            |.:|:.||..:|:|.|
Human   290 LQLSEEWFYAHIIPFL 305

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ppt1	NP_001285024.1	Abhydrolase	38..311	CDD:304388	152/274 (55%)
PPT1	NP_000301.1	Abhydrolase	28..305	CDD:328752	152/274 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165143152
Domainoid	1	1.000	294	1.000	Domainoid score	I1499
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H7488
Inparanoid	1	1.050	314	1.000	Inparanoid score	I2571
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54894
OrthoDB	1	1.010	-	-		D463334at33208
OrthoFinder	1	1.000	-	-		FOG0002319
OrthoInspector	1	1.000	-	-		oto90628
orthoMCL	1	0.900	-	-		OOG6_102448
Panther	1	1.100	-	-	LDO	PTHR11247
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R8690
SonicParanoid	1	1.000	-	-		X458
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	14	13.940