DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ppt1 and pdf1

DIOPT Version :9

Sequence 1:	NP_001285024.1	Gene:	Ppt1 / 31805	FlyBaseID:	FBgn0030057	Length:	314	Species:	Drosophila melanogaster
Sequence 2:	NP_595325.2	Gene:	pdf1 / 2540904	PomBaseID:	SPBC530.12c	Length:	622	Species:	Schizosaccharomyces pombe

Alignment Length:	309	Identity:	106/309 - (34%)
Similarity:	161/309 - (52%)	Gaps:	34/309 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 SCILFLLFLIFSLVLSYIWWSPTKGGTNP----------------EVLPVVLWHGMGDTCCVPFS 58
            ||..||:|.:||.||     .|.|....|                |.||||:|||:||| ...|:
pombe     3 SCSSFLIFFLFSWVL-----LPMKSFAIPIISLDKVRLAINDGASEQLPVVIWHGLGDT-PTSFT 61

  Fly    59 LGAIMNLIVEQTKGGYVRSLQIGGNVLIDWQSGFFIHPNEQVDYVCKQLLQDEHLAKGYHAIGFS 123
            |..:...:.:.|||. |.::::|.|...|.::|:.....:|:|.||..:..::.|:.|::|:|.|
pombe    62 LTEVSQRVQKLTKGA-VYAIRVGDNEFEDIKAGYLGKLEDQLDEVCDLIGNEDSLSNGFYALGLS 125

  Fly   124 QGGQFLRAVAERCPNPPMRNLITLGGQHQGIFGLPMCPTLTEKPCDYITR-LLDNAAYAPEVQKA 187
            |||.||||:|:.|....:|:|||||..|.||..:|.| :.|...|..:.. :|....:...:|..
pombe   126 QGGLFLRALAQTCDAAKIRSLITLGSPHSGINTIPGC-SPTNLICKAVVHSILGLGIWHSWIQNH 189

  Fly   188 LVQATYWHDPIMENKYRLGSTFLADINNELFINKFYIENLQKLKK---FVMVQFLNDTIVQPKES 249
            :|||.|:......:||...:.||..:|||: ::..|..|::|||:   .|.|.|..|.||:|..|
pombe   190 VVQAQYYRTEKQYDKYLENNKFLTHLNNEV-LHDNYTRNIEKLKELDNLVAVSFERDDIVEPPYS 253

  Fly   250 QWFQYY--TTGQNKVIQPFTESKVYQDLGLDKMHRQGQLVFLGVEGDHL 296
            ..|.:.  |||:|..::.|.   :|:.|||..:..||:|..:...|.||
pombe   254 TGFGWINETTGENIEMEDFV---LYESLGLKDLVNQGKLETISFPGRHL 299

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ppt1	NP_001285024.1	Abhydrolase	38..311	CDD:304388	95/281 (34%)
pdf1	NP_595325.2	Abhydrolase	45..314	CDD:304388	93/262 (35%)
		PgpB	406..578	CDD:223743
		PAP2_dolichyldiphosphatase	415..568	CDD:239477
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	142	1.000	Domainoid score	I1192
eggNOG	1	0.900	-	-		E1_COG1075
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H7488
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002319
OrthoInspector	1	1.000	-	-		oto101599
orthoMCL	1	0.900	-	-		OOG6_102448
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R8690
SonicParanoid	1	1.000	-	-		X458
TreeFam	1	0.960	-	-
	10	9.700