Protein Alignment mthl14 and mthl13

DIOPT Version :9

• Sequence 1: NP_728509.1
• Gene: mthl14 / 318046
• FlyBaseID: FBgn0052476
• Length: 533
• Species: Drosophila melanogaster
• Sequence 2: NP_788325.2
• Gene: mthl13 / 246395
• FlyBaseID: FBgn0050018
• Length: 440
• Species: Drosophila melanogaster
• Alignment Length: 510
• Identity: 107/510 - (20%)
• Similarity: 178/510 - (34%)
• Gaps: 194/510 - (38%)

  Fly    86 VQSPVDNPLDPADCSQREKYRKQPVATPSSRLRKCCPHGENLNIYRENQSDSMCDNGLLSFEPTI 150
            |:|..||..|..|.     :...|:         |||        |:|    |..||..||:..:
  Fly    33 VKSDDDNSNDEDDL-----WHCIPI---------CCP--------RKN----MMANGGCSFKEHL 71

  Fly   151 ------ISAVLFDNCIEDLEVETTLDYDIGNPCNSSLL---YDDKD-------DVFFVLQDGSLL 199
                  ::..|.||..|.|...           |.:||   :.|.|       |.:.:.::|::.
  Fly    72 FRTKLDLNIRLDDNSTEALYFN-----------NQTLLITSFWDIDEMMGLRRDEYTLYKNGTIY 125

  Fly   200 IIDKFGNESYTVKEHYCL-------DIDKS----GHLFAFTCVTQVEEQIAFAKVVFVAVLMLIS 253
            |   ..::|...||.||.       |..::    .|.|     :.:|...||.       |...|
  Fly   126 I---HSDQSIQTKEEYCFYPHQIYSDFPETIWIISHKF-----SSIESPGAFE-------LASGS 175

  Fly   254 MPCLLLVSYLHMTLRLLRNLHGLSLSLMSLCLASGYFVHSVVHIYGIPNQGFIGYVI-------- 310
            :.|.:::..:::.::.|||..|..:.....||                   |:.|:|
  Fly   176 IICYIIIFGIYLFVKELRNDFGKCVMSCVFCL-------------------FLDYLIWLMDELRL 221

  Fly   311 --QFCILSYFFWYLCICFNVLLNVWYK-LPCCIQCSKSWATF----------NFACYAVFAFSGP 362
              .||.|:   .|:...|:...:||:. :..||     |...          .|..|:.||:...
  Fly   222 LDDFCSLT---GYIMFFFDFANSVWFSIISYCI-----WKKITSVVSQENRDQFVFYSTFAYGIS 278

  Fly   363 ATIVALTVQ------------KGLPGMPSYFLQGLTE-SIRDSQR-----YFIPPVSTILFLSFL 409
            |..:.:.:.            ..||      |.|.:. |:.|.:|     ||:|     ..:...
  Fly   279 AIPLGIIISINQFWEEDLRKWNWLP------LVGFSRCSVDDCKRSSWVYYFVP-----YAIMCA 332

  Fly   410 LNIISFFGFQRISGYAKAEKNIQERKCLFDQQKYEDVKKDAKCVSLLGIIMVVSWLLEIITFYSG 474
            :|||.|  ...|....|.::|      |.:..|..|  ::..||:       |::|
  Fly   333 INIIMF--VLTIKHIMKTKRN------LHNLTKRPD--RNETCVT-------VNFL--------- 371

  Fly   475 SNSNYLILCDMVNGLQGV-WVLLIFLVVRRRRTIILRWWYDRGSHEIEGTELQAL 528
             |....:|...::|:.|| |:|:|||::....|    :|      :|.|..:|.:
  Fly   372 -NFELYLLFLRISGIMGVAWILIIFLLIEVNST----FW------DIFGIIIQQI 415

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mthl14	NP_728509.1	7tmB3_Methuselah-like	239..512	CDD:320167	64/312 (21%)
		TM helix 1	241..266	CDD:320167	3/24 (13%)
		TM helix 2	275..297	CDD:320167	3/21 (14%)
		TM helix 3	306..331	CDD:320167	7/34 (21%)
		TM helix 4	349..369	CDD:320167	5/29 (17%)
		TM helix 5	389..418	CDD:320167	9/33 (27%)
		TM helix 6	445..472	CDD:320167	5/26 (19%)
		TM helix 7	477..502	CDD:320167	9/25 (36%)
mthl13	NP_788325.2	Mth_Ecto	<49..158	CDD:299804	30/143 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462173
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840