DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tengl2 and Exog

DIOPT Version :9

Sequence 1:	NP_722779.1	Gene:	Tengl2 / 318044	FlyBaseID:	FBgn0052463	Length:	318	Species:	Drosophila melanogaster
Sequence 2:	XP_006244150.2	Gene:	Exog / 301062	RGDID:	1304628	Length:	443	Species:	Rattus norvegicus

Alignment Length:	227	Identity:	87/227 - (38%)
Similarity:	125/227 - (55%)	Gaps:	6/227 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    77 KFGFP--GLDDLRLYSDFVLSYDRRNRVAHWVCEHLQADSIHPNRGRRGRNPYQPDLSVPSNFRS 139
            :||||  | .:.|.|::..||||:..||..||.||:..|.|..:..|: ...::||.:|||.|.:
  Rat   139 QFGFPLTG-TETRRYTNHALSYDQAKRVPRWVLEHISKDKIIGDADRK-HCKFKPDPTVPSAFSA 201

  Fly   140 ELSDYRRSGFDRGHLAAAGNHHLQQNHCEDTFFLTNIAPQVGQGFNRSAWNNLEQYVRNLVHRFG 204
            ...||..||:.|||:|.|||:........:||:|:||.||..:. |...||.:|.|.|.|..||.
  Rat   202 LNEDYIGSGWSRGHMAPAGNNKFSSEAMAETFYLSNIVPQNFEN-NSGYWNRIEMYCRELTERFE 265

  Fly   205 SVFVCTGPLYKPNQRPGGKWAVEYEMIGLNMVAVPTHFFKVIMVESKLHLGKPYMEG-YVLPNAP 268
            .|::.:|||..|:.|..|...|.|::||.:.||||:|.:|||:........:|...| :|:||..
  Rat   266 DVWIVSGPLTLPHTRNDGTKTVSYQVIGEDNVAVPSHLYKVILARRSPESTEPLALGAFVVPNKA 330

  Fly   269 IPDGLPLRSFLCDIREIEHYAGLKFFDGLRRS 300
            |.....|..|...:.::|..:||.||..|.|:
  Rat   331 IGFQSQLSEFQVSLHDLEKMSGLVFFPHLDRT 362

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tengl2	NP_722779.1	Endonuclease_NS	74..300	CDD:279553	86/225 (38%)
Exog	XP_006244150.2	NUC	152..361	CDD:214683	80/210 (38%)
Exog	XP_006244150.2	Exog_C	377..425	CDD:407864
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1864
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D570297at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820