Protein Alignment Tengl2 and Endog

DIOPT Version :9

• Sequence 1: NP_722779.1
• Gene: Tengl2 / 318044
• FlyBaseID: FBgn0052463
• Length: 318
• Species: Drosophila melanogaster
• Sequence 2: NP_031957.1
• Gene: Endog / 13804
• MGIID: 1261433
• Length: 294
• Species: Mus musculus
• Alignment Length: 220
• Identity: 103/220 - (46%)
• Similarity: 143/220 - (65%)
• Gaps: 4/220 - (1%)

  Fly    74 QIMKFGFPGLDDLRLYSDFVLSYDRRNRVAHWVCEHLQADSIHPNRGRRGRNPYQPDLSVPSNFR 138
            ::.|:|.||:..||....:|||||.|.|.|.||.|.|:.:.:..: |.|....::.|.||.:..|
Mouse    60 ELAKYGLPGVAQLRSRESYVLSYDPRTRGALWVLEQLRPERLRGD-GDRSACDFREDDSVHAYHR 123

  Fly   139 SELSDYRRSGFDRGHLAAAGNHHLQQNHCEDTFFLTNIAPQVGQGFNRSAWNNLEQYVRNLVHRF 203
            :..:|||.|||||||||||.||...|...:|||:|:|:||||.. .|::||||||:|.|:|...:
Mouse   124 ATNADYRGSGFDRGHLAAAANHRWSQRAMDDTFYLSNVAPQVPH-LNQNAWNNLERYSRSLTRTY 187

  Fly   204 GSVFVCTGPLYKPNQRPGGKWAVEYEMIGLNMVAVPTHFFKVIMVESKLHLGKPYMEGYVLPNAP 268
            .:|:||||||:.|.....||..|:|::||.|.||||||||||:::|:.  .|:..:..||:||||
Mouse   188 QNVYVCTGPLFLPRTEADGKSYVKYQVIGKNHVAVPTHFFKVLILEAA--GGQIELRSYVMPNAP 250

  Fly   269 IPDGLPLRSFLCDIREIEHYAGLKF 293
            :.:.:||..||..|..||..:||.|
Mouse   251 VDETIPLERFLVPIESIERASGLLF 275

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tengl2	NP_722779.1	Endonuclease_NS	74..300	CDD:279553	103/220 (47%)
Endog	NP_031957.1	NUC1	29..278	CDD:224777	103/220 (47%)
		NUC	75..281	CDD:214683	97/205 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167836842
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1864
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S973
OMA	1	1.010	-	-		QHG52002
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003231
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR13966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3743
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.760