DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CAH3 and Ca14

DIOPT Version :9

Sequence 1:	NP_001259349.1	Gene:	CAH3 / 31804	FlyBaseID:	FBgn0030056	Length:	250	Species:	Drosophila melanogaster
Sequence 2:	NP_001103125.1	Gene:	Ca14 / 791259	RGDID:	1599277	Length:	337	Species:	Rattus norvegicus

Alignment Length:	243	Identity:	72/243 - (29%)
Similarity:	116/243 - (47%)	Gaps:	19/243 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 QSPIEISNRAIEHIDDVDPLEYHGH----WEPVGVARVQNTGTSAMVTFSKRKQQPYIIGGALEQ 64
            ||||:|....:....|:..::.||:    .||:.   :.|.|.:..::.     .|.:..|.|.:
  Rat    45 QSPIDIQTDGVIFDPDLPTVQPHGYDQLGTEPLD---LHNNGHTVQLSL-----PPTLHLGGLPR 101

  Fly    65 DMYVFEQLHFHWSDCDE-SGCEHTLEGMKYSMEAHAVHYNSK-YKDFTEAKNKPDGLAVVAFFIQ 127
             .|...|||.||..... .|.||.:.....:.|.|.|||:|: |...:||..||.||||:...|:
  Rat   102 -KYTAAQLHLHWGQKGTLKGSEHQINSEATAAELHVVHYDSESYGSLSEAAQKPQGLAVLGILIE 165

  Fly   128 ACGEKDCPEFKKITEGIRIVQKIHTSASLDSDCLSWIGLQELSKHYYTYKGSLTTAPYFESVTWI 192
            . ||.:.|.:..|...:..|:......|:....:..:..|:| :.::.|.|||||.|.::||.|.
  Rat   166 V-GETENPAYDHILSHLHEVRYKDQKTSVPPFNVRELLPQQL-EQFFRYNGSLTTPPCYQSVLWT 228

  Fly   193 IYRTPIYVSRGQVQVFR-NLQSCPKDESKKIVNNYREIQRPHKDPEIF 239
            ::.....:|.||::..: .|.|..:|.|:.:|.||| :.:|.....||
  Rat   229 VFNRRAQISMGQLEKLQETLSSTEEDPSEPLVQNYR-VPQPLNQRTIF 275

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CAH3	NP_001259349.1	alpha_CA	4..233	CDD:238200	69/235 (29%)
Ca14	NP_001103125.1	alpha_CA_XII_XIV	29..278	CDD:239400	72/243 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3338
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1377476at2759
OrthoFinder	1	1.000	-	-		FOG0000047
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.820