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Protein Alignment CAH3 and CA12

DIOPT Version :9

Sequence 1:	NP_001259349.1	Gene:	CAH3 / 31804	FlyBaseID:	FBgn0030056	Length:	250	Species:	Drosophila melanogaster
Sequence 2:	NP_001209.1	Gene:	CA12 / 771	HGNCID:	1371	Length:	354	Species:	Homo sapiens

Alignment Length:	237	Identity:	74/237 - (31%)
Similarity:	122/237 - (51%)	Gaps:	19/237 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 VQSPIEISNRAIEHIDDVDPLEYHGHWEPVGVAR---VQNTGTSAMVTFSKRKQQPYIIGGALEQ 64
            :||||::.:..:::...:.|||:.|:  .:...:   :.|.|.|..:..   ....:|.|   .|
Human    54 LQSPIDLHSDILQYDASLTPLEFQGY--NLSANKQFLLTNNGHSVKLNL---PSDMHIQG---LQ 110

  Fly    65 DMYVFEQLHFHWSD-CDESGCEHTLEGMKYSMEAHAVHYNSK-YKDFTEAKNKPDGLAVVAFFIQ 127
            ..|...|||.||.: .|..|.|||:.|..::.|.|.|||||. |.|.:.|.||.:||||:|..|:
Human   111 SRYSATQLHLHWGNPNDPHGSEHTVSGQHFAAELHIVHYNSDLYPDASTASNKSEGLAVLAVLIE 175

  Fly   128 ACGEKDCPEFKKITEGIRIVQKIHTSASLDSDCLSWIGLQELSKHYYTYKGSLTTAPYFESVTWI 192
             .|..: |.:.||...::.|:.....|.:....:..: |.|.:..||.|:|||||.|...:|.|.
Human   176 -MGSFN-PSYDKIFSHLQHVKYKGQEAFVPGFNIEEL-LPERTAEYYRYRGSLTTPPCNPTVLWT 237

  Fly   193 IYRTPIYVSRGQVQVFRNLQSCP--KDES-KKIVNNYREIQR 231
            ::|.|:.:|:.|:........|.  .|.| ::::||:|::|:
Human   238 VFRNPVQISQEQLLALETALYCTHMDDPSPREMINNFRQVQK 279

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.