Protein Alignment CAH3 and CA5A

DIOPT Version :10

• Sequence 1: NP_572497.1
• Gene: CAH3 / 31804
• FlyBaseID: FBgn0030056
• Length: 250
• Species: Drosophila melanogaster
• Sequence 2: NP_001730.1
• Gene: CA5A / 763
• HGNCID: 1377
• Length: 305
• Species: Homo sapiens
• Alignment Length: 258
• Identity: 90/258 - (34%)
• Similarity: 124/258 - (48%)
• Gaps: 29/258 - (11%)

  Fly     4 QSPIEISNRAIEHIDDVDPLEYHGHWEPVGVARVQNTGTSAMVTFSKRKQQPYIIGGALEQDMYV 68
            ||||.|..|...:...:.||..  .:|......:.|||....|.|....:...|.||.|| :.|.
Human    64 QSPINIQWRDSVYDPQLKPLRV--SYEAASCLYIWNTGYLFQVEFDDATEASGISGGPLE-NHYR 125

  Fly    69 FEQLHFHWSDCDESGCEHTLEGMKYSMEAHAVHYNS-KYKDFTEAKNKPDGLAVVAFFIQACGEK 132
            .:|.||||...:|.|.|||::|..|..|.|.||:|| ||:::.||....:||||:..|::.....
Human   126 LKQFHFHWGAVNEGGSEHTVDGHAYPAELHLVHWNSVKYQNYKEAVVGENGLAVIGVFLKLGAHH 190

  Fly   133 D--------CPEFKKITEGIRIVQKIHTSASLDSDCLSWIGLQELSKHYYTYKGSLTTAPYFESV 189
            .        .||.|.  :..|...:....::|...|  |        .|:||.|||||.|..|||
Human   191 QTLQRLVDILPEIKH--KDARAAMRPFDPSTLLPTC--W--------DYWTYAGSLTTPPLTESV 243

  Fly   190 TWIIYRTPIYVSRGQVQVFRNLQ-SCPKDESKKIVNNYREIQRPHKDPEI---FFARNTNPKS 248
            ||||.:.|:.|:..|:..||.|. |...:|.|.:|||||.:| |..:.::   |.|.|...:|
Human   244 TWIIQKEPVEVAPSQLSAFRTLLFSALGEEEKMMVNNYRPLQ-PLMNRKVWASFQATNEGTRS 305

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CAH3	NP_572497.1	alpha_CA	4..233	CDD:238200	85/238 (36%)
CA5A	NP_001730.1	alpha_CA_V	61..296	CDD:239392	86/247 (35%)