Protein Alignment CAH3 and CA4

DIOPT Version :9

• Sequence 1: NP_001259349.1
• Gene: CAH3 / 31804
• FlyBaseID: FBgn0030056
• Length: 250
• Species: Drosophila melanogaster
• Sequence 2: XP_005257696.1
• Gene: CA4 / 762
• HGNCID: 1375
• Length: 336
• Species: Homo sapiens
• Alignment Length: 260
• Identity: 73/260 - (28%)
• Similarity: 115/260 - (44%)
• Gaps: 43/260 - (16%)

  Fly     4 QSPIEISNRAIEHIDDVDPLEYHGH-----WEPVGVARVQNTGTSAMVTFSKRKQQPYIIGGALE 63
            ||||.|.....:....:....:.|:     |      .|||.|.|.|:....:..   |.||.|.
Human    51 QSPINIVTTKAKVDKKLGRFFFSGYDKKQTW------TVQNNGHSVMMLLENKAS---ISGGGLP 106

  Fly    64 QDMYVFEQLHFHWSDCDESGCEHTLEGMKYSMEAHAVHYNSK--YKDFTEAKNKPDGLAVVAFFI 126
            .. |..:|||.||||....|.||:|:|..::||.|.||...|  .::..||::..|.:||:||.:
Human   107 AP-YQAKQLHLHWSDLPYKGSEHSLDGEHFAMEMHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLV 170

  Fly   127 QACGEKDCPE------------------------FKKITEGIRIVQKIHTSASL-DSDCLSWIGL 166
            : .|..:.|.                        |:.:.|.:..:.|...|.:: :|..|..:..
Human   171 E-IGRMNWPPPLAPCRLSQDPSLPFQAGTQVNEGFQPLVEALSNIPKPEMSTTMAESSLLDLLPK 234

  Fly   167 QELSKHYYTYKGSLTTAPYFESVTWIIYRTPIYVSRGQVQVFRNLQSCPKDESKKIVNNYREIQR 231
            :|..:||:.|.|||||....|.|.|.::|.||.:.|.|:..|.......|:::..:.:|.|.:|:
Human   235 EEKLRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILAFSQKLYYDKEQTVSMKDNVRPLQQ 299

  Fly   232  231
            Human   300  299

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CAH3	NP_001259349.1	alpha_CA	4..233	CDD:238200	73/260 (28%)
CA4	XP_005257696.1	alpha_CA_IV_XV_like	48..307	CDD:239391	73/260 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3338
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1377476at2759
OrthoFinder	1	1.000	-	-		FOG0000047
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18952
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.920