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Protein Alignment CAH3 and CA2

DIOPT Version :9

Sequence 1:	NP_001259349.1	Gene:	CAH3 / 31804	FlyBaseID:	FBgn0030056	Length:	250	Species:	Drosophila melanogaster
Sequence 2:	NP_000058.1	Gene:	CA2 / 760	HGNCID:	1373	Length:	260	Species:	Homo sapiens

Alignment Length:	237	Identity:	85/237 - (35%)
Similarity:	124/237 - (52%)	Gaps:	11/237 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 QSPIEISNRAIEHIDDVDPLEYHGHWEPVGVARVQNTGTSAMVTFSKRKQQPYIIGGALEQDMYV 68
            |||::|.....::...:.||..  .::.....|:.|.|.:..|.|...:.:..:.||.|: ..|.
Human    28 QSPVDIDTHTAKYDPSLKPLSV--SYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLD-GTYR 89

  Fly    69 FEQLHFHWSDCDESGCEHTLEGMKYSMEAHAVHYNSKYKDFTEAKNKPDGLAVVAFFIQACGEKD 133
            ..|.||||...|..|.|||::..||:.|.|.||:|:||.||.:|..:||||||:..|::....|
Human    90 LIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAK- 153

  Fly   134 CPEFKKITEGIRIVQKIHTSA-SLDSDCLSWIGLQELSKHYYTYKGSLTTAPYFESVTWIIYRTP 197
             |..:|:.:   ::..|.|.. |.|.......||...|..|:||.|||||.|..|.||||:.:.|
Human   154 -PGLQKVVD---VLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEP 214

  Fly   198 IYVSRGQVQVFRNLQSCPKDESKKI-VNNYREIQRPHKDPEI 238
            |.||..||..||.|....:.|.::: |:|:|..| |.|:.:|
Human   215 ISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQ-PLKNRQI 255

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.