Protein Alignment CAH3 and PTPRG

DIOPT Version :10

• Sequence 1: NP_572497.1
• Gene: CAH3 / 31804
• FlyBaseID: FBgn0030056
• Length: 250
• Species: Drosophila melanogaster
• Sequence 2: XP_016862450.1
• Gene: PTPRG / 5793
• HGNCID: 9671
• Length: 1485
• Species: Homo sapiens
• Alignment Length: 284
• Identity: 68/284 - (23%)
• Similarity: 110/284 - (38%)
• Gaps: 67/284 - (23%)

  Fly     4 QSPIEISNRAIEHIDDVDPLEYHGH--------WEPVGVARVQNTGTSAMVTFSKRKQQPYIIGG 60
            ||||:|.::.....::...|:..|.        |       ::|||.:..:..    :..|.:.|
Human    83 QSPIDILDQYARVGEEYQELQLDGFDNESSNKTW-------MKNTGKTVAILL----KDDYFVSG 136

  Fly    61 ALEQDMYVFEQLHFHWSDCDES-GCEHTLEGMKYSMEA----------------HAVHYNSKYKD 108
            |.....:..|::.|||...:.| |.||::.|.::.:||                ..:....|.:.
Human   137 AGLPGRFKAEKVEFHWGHSNGSAGSEHSINGRRFPVEAEDARGGDIMLMLSQGMRFILLGLKKEQ 201

  Fly   109 FTEAKN------------KPDG-------------LAVVAFFIQACGEKDCPEFKKITEGIRIVQ 148
            |.|.|:            .||.             :..:|.|.|. ..:|......|..|::.|.
Human   202 FEERKSWTTYQSMQIFFYNPDDFDSFQTAISENRIIGAMAIFFQV-SPRDNSALDPIIHGLKGVV 265

  Fly   149 KIHTSASLDSDCLSWIGLQELSKHYYTYKGSLTTAPYFESVTWIIYRTPIYVSRGQVQVFRNLQS 213
            .......||...|..:....|.. ||.|.|||||.|..|.|.||::|.|:.:|..|::.|.::.:
Human   266 HHEKETFLDPFVLRDLLPASLGS-YYRYTGSLTTPPCSEIVEWIVFRRPVPISYHQLEAFYSIFT 329

  Fly   214 CPKDESKKIV----NNYREIQRPH 233
            ..:.:..|.|    ||:|..||.|
Human   330 TEQQDHVKSVEYLRNNFRPQQRLH 353

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CAH3	NP_572497.1	alpha_CA	4..233	CDD:238200	67/282 (24%)
PTPRG	XP_016862450.1	alpha_CARP_receptor_like	67..359	CDD:239396	68/284 (24%)
		FN3	388..478	CDD:238020
		PHA03169	<584..>742	CDD:223003
		R-PTPc-G-1	888..1161	CDD:350505
		R-PTP-G-2	1245..1449	CDD:350508