DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CAH3 and ca16b

DIOPT Version :9

Sequence 1:	NP_001259349.1	Gene:	CAH3 / 31804	FlyBaseID:	FBgn0030056	Length:	250	Species:	Drosophila melanogaster
Sequence 2:	XP_001919055.3	Gene:	ca16b / 569183	ZFINID:	ZDB-GENE-080818-1	Length:	1382	Species:	Danio rerio

Alignment Length:	236	Identity:	66/236 - (27%)
Similarity:	109/236 - (46%)	Gaps:	11/236 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 QSPIEISNRAIEHIDDVDPLEYHGHWEPVGVAR--VQNTGTSAMVTFSKRKQQPYIIGGALEQDM 66
            |||::|.:...:...:...|...| :|.....|  ::|||.:..:..    :..|.:.||.....
Zfish    78 QSPVDILDPETQVSQECQELTLDG-FETKSSNRTTMKNTGKTVSIVL----KNDYFVRGAGLPGR 137

  Fly    67 YVFEQLHFHWSDCDES-GCEHTLEGMKYSMEAHAVHYNS-KYKDFTEAKNKPDGLAVVAFFIQAC 129
            :..|::.|||...:.| |.||::.|.|:.:|.....||| .:...:.|..:...:|.:|.|.|.
Zfish   138 FKAEKVEFHWGSTNGSAGSEHSINGKKFPVEMQIYFYNSDDFDSLSTAIKERRIIAAMAVFFQV- 201

  Fly   130 GEKDCPEFKKITEGIRIVQKIHTSASLDSDCLSWIGLQELSKHYYTYKGSLTTAPYFESVTWIIY 194
            ..||....:.|..|::.|.......:|.|..|..:....|.. ||.|.|||||.|..:.|.|||:
Zfish   202 ATKDNIAAEPIIAGLKRVVHHEKETNLGSFILRDLLPSSLGS-YYRYTGSLTTPPCSKVVEWIIF 265

  Fly   195 RTPIYVSRGQVQVFRNLQSCPKDESKKIVNNYREIQRPHKD 235
            ..|:|:|..|::.|.::.:..:.:..|.|:..|...||.:|
Zfish   266 SRPVYLSYHQLEAFYSIFTTEQQDHVKSVDYLRNNHRPIQD 306

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CAH3	NP_001259349.1	alpha_CA	4..233	CDD:238200	64/232 (28%)
ca16b	XP_001919055.3	alpha_CARP_receptor_like	62..314	CDD:239396	66/236 (28%)
		FN3	340..417	CDD:214495
		Herpes_BLLF1	450..>557	CDD:330317
		PTPc	790..1057	CDD:214550
		PTPc	1089..1347	CDD:214550
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3338
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810