DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CAH3 and ca4b

DIOPT Version :9

Sequence 1:	NP_001259349.1	Gene:	CAH3 / 31804	FlyBaseID:	FBgn0030056	Length:	250	Species:	Drosophila melanogaster
Sequence 2:	NP_001159683.1	Gene:	ca4b / 553246	ZFINID:	ZDB-GENE-080815-5	Length:	304	Species:	Danio rerio

Alignment Length:	240	Identity:	68/240 - (28%)
Similarity:	109/240 - (45%)	Gaps:	10/240 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 QSPIEISNRAIEHIDDVDPLEYHGHWEPVGVARVQNTGTSAMVTFSKRKQQPYIIGGALEQDMYV 68
            ||||.|..........:.|:::..:.|.:. |.:.|.|.:..:....|.:    |.||.....|.
Zfish    52 QSPINIVTNKASTDSRLTPVQFTDYQERLN-AVIVNNGHTVQINLPDRAK----INGANLGSTYK 111

  Fly    69 FEQLHFHWSDCDESGCEHTLEGMKYSMEAHAVHYNSKYKDFTEAKNKPDGLAVVAFFIQACGEKD 133
            .:|||.||......|.|||::|.|:.||.|.||...:|....:|.....|:||:.||.:. .|..
Zfish   112 AQQLHLHWGKNGGPGSEHTIDGEKFPMELHVVHIKEEYNSLEQAVGDSSGVAVLGFFYEE-SENA 175

  Fly   134 CPEFKKITEGIRIVQKIHTSASLDSDCLSWIGLQELSKHYYTYKGSLTTAPYFESVTWIIYRTPI 198
            ...:..|...:..:....::|.|.:..|..:...|....|:.|:|||||....|:|.|.|:...|
Zfish   176 NKNYDAIINSLTNITHPESNAELGAISLDMLIPNEDLDKYFRYEGSLTTPGCAEAVVWTIFEKTI 240

  Fly   199 YVSRGQVQVFRNLQSCPKDESKKIVNNYREIQRPHKDPEIFFARN 243
            .:|:.|:..|.||..   .:...:||.:|.||.....| ::::|:
Zfish   241 PLSKEQLSAFSNLTF---SDGAAMVNTFRPIQLRFDRP-VYYSRS 281

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CAH3	NP_001259349.1	alpha_CA	4..233	CDD:238200	66/228 (29%)
ca4b	NP_001159683.1	alpha_CA_IV_XV_like	50..278	CDD:239391	67/235 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3338
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1377476at2759
OrthoFinder	1	1.000	-	-		FOG0000047
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18952
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.920