DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CAH3 and Ca13

DIOPT Version :9

Sequence 1:	NP_001259349.1	Gene:	CAH3 / 31804	FlyBaseID:	FBgn0030056	Length:	250	Species:	Drosophila melanogaster
Sequence 2:	NP_001128465.1	Gene:	Ca13 / 499566	RGDID:	1560453	Length:	262	Species:	Rattus norvegicus

Alignment Length:	235	Identity:	85/235 - (36%)
Similarity:	125/235 - (53%)	Gaps:	21/235 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 QSPIEISNRAIEHIDDVDPLEYHGHWEPVGVARVQNTGTSAMVTFSKRKQQPYIIGGALEQDMYV 68
            ||||||..:.:::...:.||..  .::|.....:.|:|.|..|.|...:.:..:.||.| ...|.
  Rat    29 QSPIEIKTKEVKYDSSLRPLSI--KYDPASAKIISNSGHSFNVDFDDTEDKSVLRGGPL-TGSYR 90

  Fly    69 FEQLHFHWSDCDESGCEHTLEGMKYSMEAHAVHYNS-KYKDFTEAKNKPDGLAVVAFFIQACGEK 132
            ..|.|.||...|:.|.||.::|::|:.|.|.||:|| ||..|.||.::.|||||:..|:| .||.
  Rat    91 LRQFHLHWGSADDHGSEHVVDGVRYAAELHVVHWNSDKYPSFVEAAHESDGLAVLGVFLQ-IGEH 154

  Fly   133 DCPEFKKIT---EGIRIVQKIHTSASLDSDCL---SWIGLQELSKHYYTYKGSLTTAPYFESVTW 191
            : |:.:|||   :.|:...|.....:.|..||   ||        .|:||.||||..|..|||||
  Rat   155 N-PQLQKITDILDSIKEKGKQTRFTNFDPLCLLPSSW--------DYWTYPGSLTVPPLLESVTW 210

  Fly   192 IIYRTPIYVSRGQVQVFRNLQSCPKDESKK-IVNNYREIQ 230
            |:.:.||.:|..|:..||:|....:.||.. :::|:|..|
  Rat   211 IVLKQPISISSQQLARFRSLLCTAEGESAAFLLSNHRPPQ 250

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CAH3	NP_001259349.1	alpha_CA	4..233	CDD:238200	85/235 (36%)
Ca13	NP_001128465.1	alpha_CA_I_II_III_XIII	2..261	CDD:239393	85/235 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3338
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1377476at2759
OrthoFinder	1	1.000	-	-		FOG0000047
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.820