DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CAH3 and Ptprg

DIOPT Version :9

Sequence 1:NP_001259349.1 Gene:CAH3 / 31804 FlyBaseID:FBgn0030056 Length:250 Species:Drosophila melanogaster
Sequence 2:NP_033007.2 Gene:Ptprg / 19270 MGIID:97814 Length:1442 Species:Mus musculus


Alignment Length:241 Identity:64/241 - (26%)
Similarity:104/241 - (43%) Gaps:27/241 - (11%)


- Green bases have known domain annotations that are detailed below.


  Fly     4 QSPIEISNRAIEHIDDVDPLEYHGH--------WEPVGVARVQNTGTSAMVTFSKRKQQPYIIGG 60
            ||||:|.:......|:...|:..|.        |       ::|||.:..:..    :..|.:.|
Mouse    83 QSPIDILDHHARVGDEYQELQLDGFDNESSNKTW-------MKNTGKTVAILL----KDDYFVSG 136

  Fly    61 ALEQDMYVFEQLHFHWSDCDES-GCEHTLEGMKYSMEAHAVHYN-SKYKDFTEAKNKPDGLAVVA 123
            |.....:..|::.|||...:.| |.||::.|.::.:|.....|| ..:..|..|.::...:..:|
Mouse   137 AGLPGRFKAEKVEFHWGHSNGSAGSEHSVNGRRFPVEMQIFFYNPDDFDSFQTAISENRIIGAMA 201

  Fly   124 FFIQACGEKDCPEFKKITEGIRIVQKIHTSASLDSDCLSWIGLQELSKHYYTYKGSLTTAPYFES 188
            .|.|. ..:|......|..|::.|........||...|..:....|.. ||.|.|||||.|..|.
Mouse   202 IFFQV-SPRDNSALDPIIHGLKGVVHHEKETFLDPFILRDLLPASLGS-YYRYTGSLTTPPCSEI 264

  Fly   189 VTWIIYRTPIYVSRGQVQVFRNLQSCPKDESKKIV----NNYREIQ 230
            |.||::|.|:.:|..|::.|.::.:..:.:..|.|    ||:|..|
Mouse   265 VEWIVFRRPVPISYHQLEAFYSIFTTEQQDHVKSVEYLRNNFRPQQ 310

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CAH3NP_001259349.1 alpha_CA 4..233 CDD:238200 64/241 (27%)
PtprgNP_033007.2 PLN02179 17..272 CDD:177835 53/201 (26%)
alpha_CARP_receptor_like 67..319 CDD:239396 64/241 (27%)
FN3 348..438 CDD:238020
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 461..480
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 557..726
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 769..788
PTPc 844..1115 CDD:214550
PTPc 873..1115 CDD:238006
Substrate binding. /evidence=ECO:0000250 1057..1063
PTPc 1147..1405 CDD:214550
PTPc 1174..1405 CDD:238006
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1412..1442
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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