DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CAH3 and cah-6

DIOPT Version :9

Sequence 1:	NP_001259349.1	Gene:	CAH3 / 31804	FlyBaseID:	FBgn0030056	Length:	250	Species:	Drosophila melanogaster
Sequence 2:	NP_491189.1	Gene:	cah-6 / 189049	WormBaseID:	WBGene00000284	Length:	319	Species:	Caenorhabditis elegans

Alignment Length:	235	Identity:	59/235 - (25%)
Similarity:	111/235 - (47%)	Gaps:	11/235 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 QSPIEI---SNRAIEHIDDVDPLEYHGHWEPVGVARVQNTGTSAMVTFSKRKQQPYIIGGALEQD 65
            ||||:|   .....||:.:.   .:...:|..|..:..|.|.|  :...:......:....|.::
Worm    68 QSPIDIVPVITAFGEHLQNA---HFEVTYESTGEFKAVNDGNS--IWLMREGNSSELAISFLPEE 127

  Fly    66 MYVFEQLHFHWSDCDESGCEHTLEGMKYSMEAHAVHYNSKYKDFTEAKNKPDGLAVVAFFIQACG 130
            .|..:.::|||:....:|.|||:.|:.|:.|.|.:|.|:::....:|..:|:|:..:|.|:....
Worm   128 QYHLDAVNFHWATEPMNGSEHTIGGVGYAGEMHLIHRNTRFATMADALKQPNGVIAIAVFLNESH 192

  Fly   131 EKDCPEFKKITEGIRIVQKIHTSASLDSDCLSWIGLQELSKHYYTYKGSLTTAPYFESVTWIIYR 195
            :.:......|....:::.|.........|..::..:.|.:|.::.|:||.||.|:.|:|.||:.|
Worm   193 DDNAVFSPLINLLPQVIYKGSECKLCSFDFQTFFPVAEKTKEFWMYEGSETTDPFRETVNWIVIR 257

  Fly   196 TPIYVSRGQVQVFRNLQSCPKDE--SKKI-VNNYREIQRP 232
            ..:.:|..|:...|.:::...||  |.|: :...|.||.|
Worm   258 AALPISSHQLDKLREVRAGRYDEEFSDKVPMKPLRPIQNP 297

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CAH3	NP_001259349.1	alpha_CA	4..233	CDD:238200	59/235 (25%)
cah-6	NP_491189.1	alpha_CARP_receptor_like	56..304	CDD:239396	59/235 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3338
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1377476at2759
OrthoFinder	1	1.000	-	-		FOG0000047
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18952
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.920