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Protein Alignment CAH3 and CA5B

DIOPT Version :9

Sequence 1:	NP_001259349.1	Gene:	CAH3 / 31804	FlyBaseID:	FBgn0030056	Length:	250	Species:	Drosophila melanogaster
Sequence 2:	NP_009151.1	Gene:	CA5B / 11238	HGNCID:	1378	Length:	317	Species:	Homo sapiens

Alignment Length:	234	Identity:	80/234 - (34%)
Similarity:	120/234 - (51%)	Gaps:	19/234 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 QSPIEISNRAIEHIDDVDPLEYHGHWEPVGVARVQNTGTSAMVTFSKRKQQPYIIGGALEQDMYV 68
            ||||.|..|...:...:.||..  .::|.....|.|.|.|.:|.|.....:..|.||.||.: |.
Human    64 QSPINIRWRDSVYDPGLKPLTI--SYDPATCLHVWNNGYSFLVEFEDSTDKSVIKGGPLEHN-YR 125

  Fly    69 FEQLHFHWSDCDESGCEHTLEGMKYSMEAHAVHYNS-KYKDFTEAKNKPDGLAVVAFFIQACGEK 132
            .:|.||||...|..|.|||::...:..|.|.||:|: ::::|.:|..:.:||||:..|::.  .|
Human   126 LKQFHFHWGAIDAWGSEHTVDSKCFPAELHLVHWNAVRFENFEDAALEENGLAVIGVFLKL--GK 188

  Fly   133 DCPEFKKITEGIRIVQKIHTSA-----SLDSDCLSWIGLQELSKHYYTYKGSLTTAPYFESVTWI 192
            ...|.:|:.:.:..::  |..|     |.|..|     |......|:||.|||||.|..||||||
Human   189 HHKELQKLVDTLPSIK--HKDALVEFGSFDPSC-----LMPTCPDYWTYSGSLTTPPLSESVTWI 246

  Fly   193 IYRTPIYVSRGQVQVFRNLQSCPKDE-SKKIVNNYREIQ 230
            |.:.|:.|...|::.||.|....:.| .|::|:|:|.:|
Human   247 IKKQPVEVDHDQLEQFRTLLFTSEGEKEKRMVDNFRPLQ 285

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.