DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CAH3 and ca6

DIOPT Version :9

Sequence 1:	NP_001259349.1	Gene:	CAH3 / 31804	FlyBaseID:	FBgn0030056	Length:	250	Species:	Drosophila melanogaster
Sequence 2:	XP_009295179.1	Gene:	ca6 / 100006448	ZFINID:	ZDB-GENE-030131-7091	Length:	538	Species:	Danio rerio

Alignment Length:	236	Identity:	89/236 - (37%)
Similarity:	126/236 - (53%)	Gaps:	24/236 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 QSPIEISNRAIEHIDDVDPLEYHGHWEPVGVARVQNTGTSAMV----TFSKRKQQPYIIGGALEQ 64
            ||||:|..|.:.:...:..||..|:.:..|...::|.|.|..:    |....|..|:
Zfish    49 QSPIDIQRRKVRYSPRMQQLELTGYEDIRGSFLMKNNGHSVEIQLPSTMKITKGFPH-------- 105

  Fly    65 DMYVFEQLHFHWS--DCDESGCEHTLEGMKYSMEAHAVHYNS-KYKDFTEAKNKPDGLAVVAFFI 126
             .|...|:|.||.  |.:.||.|||::|::|..|.|.||||| ||..|.|||||||||||:|||.
Zfish   106 -QYTAVQMHLHWGGWDLEASGSEHTMDGIRYMAELHVVHYNSEKYPSFEEAKNKPDGLAVLAFFF 169

  Fly   127 QACGEKDCPEFKKITEGIRIVQKIHTSASLDS-DCLSWIGLQELSKHYYTYKGSLTTAPYFESVT 190
            :. |..:...:......:..::.:..|.|:.: :.||.  |.|...|:|.|||||||.|.||||.
Zfish   170 ED-GHFENTYYSDFISNLANIKYVGQSMSISNLNVLSM--LSENLSHFYRYKGSLTTPPCFESVM 231

  Fly   191 WIIYRTPIYVSRGQVQVFRNLQSCPKD-ESKKIVNNYREIQ 230
            |.::.|||.:|..|:   |.|:|...| ::|.:.|:||..|
Zfish   232 WTVFDTPITLSHNQI---RKLESTLMDHDNKTLWNDYRMAQ 269

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CAH3	NP_001259349.1	alpha_CA	4..233	CDD:238200	89/236 (38%)
ca6	XP_009295179.1	alpha_CA	33..281	CDD:320708	89/236 (38%)
ca6	XP_009295179.1	LamG	332..521	CDD:328935
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3338
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1377476at2759
OrthoFinder	1	1.000	-	-		FOG0000047
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.820