Protein Alignment CG32454 and XPNPEP2

DIOPT Version :10

• Sequence 1: NP_730740.1
• Gene: CG32454 / 318037
• FlyBaseID: FBgn0260481
• Length: 534
• Species: Drosophila melanogaster
• Sequence 2: NP_003390.4
• Gene: XPNPEP2 / 7512
• HGNCID: 12823
• Length: 674
• Species: Homo sapiens
• Alignment Length: 303
• Identity: 53/303 - (17%)
• Similarity: 98/303 - (32%)
• Gaps: 74/303 - (24%)

  Fly   113 EPHRKNRIFSHVLVVAGADSARSYPFRQRP----DFLYLCDCLRPGAALVLTRSRKRNTGALLFL 173
            :.|:|  :.:.||:.|..::|..:..|...    .|.|....|...:..:.....:.::..|.:|
Human   228 QKHQK--VPTAVLLSALEETAWLFNLRASDIPYNPFFYSYTLLTDSSIRLFANKSRFSSETLSYL 290

  Fly   174 SQDVDSQLSTIFSHMHYVDDVLPLAMLKKSLLWLLRDHSPELWHFY----------DPSSPVSCI 228
            :......:.........|.|.:....|....:|:...::  ::..|          |..|||
Human   291 NSSCTGPMCVQIEDYSQVRDSIQAYSLGDVRIWIGTSYT--MYGIYEMIPKEKLVTDTYSPV--- 350

  Fly   229 VQEVANEAKIPMGNPRYILQYTRTVKTSRELRALRRANATAADSM-------------------- 273
                               ..|:.||.|:|...|:.::...|.::
Human   351 -------------------MMTKAVKNSKEQALLKASHVRDAVAVIRYLVWLEKNVPKGTVDEFS 396

  Fly   274 -AEVIAQHHQIPQ-------ELAASFDYKCRLRHARPDVTKTSCGLDGNGLWQMDAGCQYGGYEG 330
             ||::.:.....|       |..::......|.|..| ..:.:..|..:.::.:|:|.||.....
Human   397 GAEIVDKFRGEEQFSSGPSFETISASGLNAALAHYSP-TKELNRKLSSDEMYLLDSGGQYWDGTT 460

  Fly   331 GLARC--WPSSGRFTPPQKMIYGALLDMRRDLCSLIQYAGCEG 371
            .:.|.  |.:...|   ||..|..:|....||..||..|...|
Human   461 DITRTVHWGTPSAF---QKEAYTRVLIGNIDLSRLIFPAATSG 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32454	NP_730740.1	AMP_N	106..223	CDD:198079	18/123 (15%)
		APP_MetAP	259..468	CDD:469704	27/143 (19%)
XPNPEP2	NP_003390.4	Creatinase_N	54..184	CDD:460159
		Creatinase_N_2	195..361	CDD:465053	25/158 (16%)
		APP	365..583	CDD:238518	27/140 (19%)
		Peptidase_M24_C	585..648	CDD:465052