Protein Alignment CG32454 and PEPD

DIOPT Version :10

• Sequence 1: NP_730740.1
• Gene: CG32454 / 318037
• FlyBaseID: FBgn0260481
• Length: 534
• Species: Drosophila melanogaster
• Sequence 2: NP_000276.2
• Gene: PEPD / 5184
• HGNCID: 8840
• Length: 493
• Species: Homo sapiens
• Alignment Length: 500
• Identity: 99/500 - (19%)
• Similarity: 166/500 - (33%)
• Gaps: 168/500 - (33%)

  Fly   116 RKNRIF--SHVLVVAGADSARSY------PFRQRPDFLYLCDCLRPGAALVLTRSRKRNTGALLF 172
            |||...  ..::|:.|.:..:.|      .|||...|.:......||...|:
Human    35 RKNPAVQAGSIVVLQGGEETQRYCTDTGVLFRQESFFHWAFGVTEPGCYGVI------------- 86

  Fly   173 LSQDVDSQLSTIF------SH---------------------MHYVDDVLP-LAMLKKSLLWLLR 209
               |||:..||:|      ||                     :.|||::.. |...|.|:|..||
Human    87 ---DVDTGKSTLFVPRLPASHATWMGKIHSKEHFKEKYAVDDVQYVDEIASVLTSQKPSVLLTLR 148

  Fly   210 DHSPELWHFYDPSSPVSCIVQEVANEAKIPMGN----PRYILQYTRTVKTSRELRALRRANATAA 270
            .        .:..|...|........:|..:.|    |..:  ..|..||..||..||..|..::
Human   149 G--------VNTDSGSVCREASFDGISKFEVNNTILHPEIV--ECRVFKTDMELEVLRYTNKISS 203

  Fly   271 DSMAEVI--AQHHQIPQELAASFDYKCRLRHARPDVTKTS----CG------------------- 310
            ::..||:  .:......||.:.|::.|   ::|..:..:|    ||
Human   204 EAHREVMKAVKVGMKEYELESLFEHYC---YSRGGMRHSSYTCICGSGENSAVLHYGHAGAPNDR 265

  Fly   311 -LDGNGLWQMDAGCQYGGYEGGLARCWPSSGRFTPPQKMIYGALL-----------------DMR 357
             :....:...|.|.:|..:...:...:|::|:||..||.:|.|:|                 ||.
Human   266 TIQNGDMCLFDMGGEYYCFASDITCSFPANGKFTADQKAVYEAVLRSSRAVMGAMKPGVWWPDMH 330

  Fly   358 R-----DLCSLIQYAGCEGAVRTPLELHAAYLIL-------LARHLRELRVLPKGVSSAAETVEL 410
            |     .|..|.......|:|...::.|...:.:       |...:.::...|:||..
Human   331 RLADRIHLEELAHMGILSGSVDAMVQAHLGAVFMPHGLGHFLGIDVHDVGGYPEGVER------- 388

  Fly   411 ARKYNCSPVVVSHVGLGKRDTSRRLLDYPFAPGNVMSLRLSISIPD------------------D 457
                      :...||....|:|.|     .||.|:::...|...|                  :
Human   389 ----------IDEPGLRSLRTARHL-----QPGMVLTVEPGIYFIDHLLDEALADPARASFLNRE 438

  Fly   458 CCQAYPEFRGILCQLGDTLHVRDDYSVDLLTAACPSEPQDIEVCL 502
            ..|.:..|.|:  ::.:.:.|.|. .::|||.. |...::||.|:
Human   439 VLQRFRGFGGV--RIEEDVVVTDS-GIELLTCV-PRTVEEIEACM 479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32454	NP_730740.1	AMP_N	106..223	CDD:198079	30/142 (21%)
		APP_MetAP	259..468	CDD:469704	50/281 (18%)
PEPD	NP_000276.2	AMP_N	18..155	CDD:198079	30/143 (21%)
		Prolidase	192..467	CDD:238520	55/302 (18%)