DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG42272 and Prpf39

DIOPT Version :9

Sequence 1:NP_729101.2 Gene:CG42272 / 318020 FlyBaseID:FBgn0259167 Length:584 Species:Drosophila melanogaster
Sequence 2:NP_808474.2 Gene:Prpf39 / 328110 MGIID:104602 Length:665 Species:Mus musculus


Alignment Length:373 Identity:68/373 - (18%)
Similarity:117/373 - (31%) Gaps:129/373 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly    81 NTSSNASRNDHMVQNNENPASFEQQTLQLQQQQQQATVQ-YAHISPLDKEVVERLIKQWAPIVWL 144
            |:.:.::.|...|...|:| .|..:.:.:.:.:|..... .||.|..:.|:..      |..:.:
Mouse    11 NSDNGSTGNSSEVAVVEHP-DFSTEIMNVTEMEQSPDASPSAHASTEENEMAN------AVNLPV 68

  Fly   145 APEEKFMPLGVEEFLQYV--HPMDKDSSFRPGVPFREY-STKSHLVTNNEVQELLGNDKSFLYG- 205
            ...|...|...|:|.:.|  :|.|    |...|...:| ..::||:...:..:.......:.|| 
Mouse    69 TEAEGDFPPEFEKFWKTVEMNPQD----FTGWVYLLQYVEQENHLMAARKAFDKFFVHYPYCYGY 129

  Fly   206 ---------RNPN-EKAVPIYGVVNLCPSTRAPAMPVVPTTPPTTTRGVY-IPVSIDPL------ 253
                     |:.| :::..:|                        .||:. ||:|:|..      
Mouse   130 WKKYADLEKRHDNIKQSDEVY------------------------RRGLQAIPLSVDLWIHYINF 170

  Fly   254 ---------EERNDTIR--------------RSSRLFPLFQRVKRESPTVPQYNQLNEYEELVME 295
                     :|.|.|||              ||.:|:.::...:.|...:.:...:  |:.::..
Mouse   171 LKETLDPGDQETNTTIRGTFEHAVLAAGTDFRSDKLWEMYINWENEQGNLREVTAV--YDRILGI 233

  Fly   296 ATQ---------KPSVQQDSEPEPENGVPVNNFIANLADNVKFSGGTYP--DD------------ 337
            .||         |..||.:...:...|.........||.....||...|  ||            
Mouse   234 PTQLYSHHFQRFKEHVQNNLPRDLLTGEQFIQLRRELASVNGHSGDDGPPGDDLPSGIEDITDPA 298

  Fly   338 ---------------------NLEENSIGQAPEKEEGPGKGKLPGFHV 364
                                 |..|:.:.:....|||.   |.|.|||
Mouse   299 KLITEIENMRHRIIEIHQEMFNYNEHEVSKRWTFEEGI---KRPYFHV 343

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG42272NP_729101.2 DUF946 <367..>437 CDD:283705
Prpf39NP_808474.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..28 3/16 (19%)
RNA14 68..>538 CDD:227438 56/309 (18%)
HAT 1 107..139 4/31 (13%)
HAT 2 141..173 8/55 (15%)
HAT 3 181..216 8/34 (24%)
HAT 4 218..251 5/34 (15%)
HAT 6 365..397
HAT 7 402..434
TPR repeat 453..481 CDD:276809
TPR repeat 486..520 CDD:276809
TPR repeat 525..555 CDD:276809
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 599..625
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167833324
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.930

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