Protein Alignment oc and pitx2

DIOPT Version :10

• Sequence 1: NP_001356934.1
• Gene: oc / 31802
• FlyBaseID: FBgn0004102
• Length: 664
• Species: Drosophila melanogaster
• Sequence 2: NP_001017227.1
• Gene: pitx2 / 549981
• XenbaseID: XB-GENE-482492
• Length: 345
• Species: Xenopus tropicalis
• Alignment Length: 322
• Identity: 90/322 - (27%)
• Similarity: 126/322 - (39%)
• Gaps: 98/322 - (30%)

  Fly    14 HPHSYGGPHPHHSVPHGPLPPGMPMP----------SLGPFGLPHGLEAVGFSQGMWGVNT---- 64
            |.|.....|.||...|.......|.|          |||        :..|..:....|:|
 Frog    27 HHHQQHQQHQHHHQQHHHQQHQQPQPQAVTLVSMASSLG--------QRSGECKARLEVHTISDT 83

  Fly    65 ---------------------------RKQRRERTTFTRAQLDVLEALFGKTRYPDIFMREEVAL 102
                                       ::|||:||.||..||..|||.|.:.||||:..|||:|:
 Frog    84 SSPEAADKDKSHQSKNEDSSTDDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAV 148

  Fly   103 KINLPESRVQVWFKNRRAKCRQQLQQQQ----------QSNSL---------SSSKN--ASGGGS 146
            ..||.|:||:|||||||||.|::.:.||          |.|.|         |.|.|  |:.|.:
 Frog   149 WTNLTEARVRVWFKNRRAKWRKRERNQQAELCKNGFGPQFNGLMQPYDDMYPSYSYNNWAAKGLT 213

  Fly   147 GNSCSSSSANSRSNSNNNGSSSNNNTQSSGGNNSNKSSQKQGNSQSSQQGGGSSGGNNSNN---- 207
            ..|.|:.|....::.|.|..||  .:..|..|:.:..|...|...|:..|...||.|:.||
 Frog   214 SASLSTKSFPFFNSMNVNPLSS--QSMFSSPNSISSMSMSSGMVPSAVTGVPGSGLNSLNNLNNL 276

  Fly   208 -----NSAAAAASAA---------------AAVAAAQSIKTHHSSFLSAAAAAASGGTNQSA 249
                 |:|...::..               :::|:.:.....||||  ..|:..:.|:|.||
 Frog   277 SNPSLNTAVPTSACPYAPPTPPYVYRDTCNSSLASLRLKAKQHSSF--GYASVQNPGSNLSA 336

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
oc	NP_001356934.1	Homeodomain	68..123	CDD:459649	34/54 (63%)
pitx2	NP_001017227.1	Homeodomain	114..170	CDD:459649	34/55 (62%)
		OAR	303..320	CDD:461067	1/16 (6%)