Protein Alignment oc and otx2

DIOPT Version :10

• Sequence 1: NP_001356934.1
• Gene: oc / 31802
• FlyBaseID: FBgn0004102
• Length: 664
• Species: Drosophila melanogaster
• Sequence 2: XP_012823826.1
• Gene: otx2 / 548931
• XenbaseID: XB-GENE-485220
• Length: 306
• Species: Xenopus tropicalis
• Alignment Length: 261
• Identity: 109/261 - (41%)
• Similarity: 130/261 - (49%)
• Gaps: 54/261 - (20%)

  Fly    35 GMPM--PSLG-PFGLPHGLEAVGFSQGMWGVNTRKQRRERTTFTRAQLDVLEALFGKTRYPDIFM 96
            ||.:  ||:| |..| |....:..|...:....||||||||||||||||||||||.|||||||||
 Frog    21 GMDLLHPSVGYPVAL-HQSRQITCSFYDFAATPRKQRRERTTFTRAQLDVLEALFAKTRYPDIFM 84

  Fly    97 REEVALKINLPESRVQVWFKNRRAKCRQQLQQQQQ--SNSLSSSK---------NASGGGSGN-- 148
            |||||||||||||||||||||||||||||.||||.  .|.:..||         ::..|.||.
 Frog    85 REEVALKINLPESRVQVWFKNRRAKCRQQQQQQQNGGQNKVRPSKKKPSPAREVSSESGTSGQFS 149

  Fly   149 -SC-------SSSSAN----------------SRSNSNNNGSSSNNNTQSSGGNNSNKSSQKQGN 189
             .|       |||:|.                |.|:|....|.....||:||        ..||.
 Frog   150 PPCSTSVPVISSSTAPVSIWSPASISPLSDPLSTSSSCMQRSYPMTYTQASG--------YSQGY 206

  Fly   190 SQSSQQGGGSSGGN-----NSNNNSAAAAASAAAAVAAAQSIKTHHSSFLSAAAAAASGGTNQSA 249
            :.|:...||...|:     :...:.|.|..|.....|....:....::..|.|..|:|.|.|.:|
 Frog   207 AGSTSYFGGMDCGSYLTPMHHQLSGAGATLSPMGTNAVTSHLNQSPAALSSQAYGASSLGFNSTA 271

  Fly   250 N 250
            :
 Frog   272 D 272

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
oc	NP_001356934.1	Homeodomain	68..123	CDD:459649	53/54 (98%)
otx2	XP_012823826.1	Homeodomain	56..111	CDD:459649	53/54 (98%)
		TF_Otx	170..251	CDD:427350	18/88 (20%)