Protein Alignment oc and PITX1

DIOPT Version :10

• Sequence 1: NP_001356934.1
• Gene: oc / 31802
• FlyBaseID: FBgn0004102
• Length: 664
• Species: Drosophila melanogaster
• Sequence 2: XP_047273274.1
• Gene: PITX1 / 5307
• HGNCID: 9004
• Length: 348
• Species: Homo sapiens
• Alignment Length: 298
• Identity: 86/298 - (28%)
• Similarity: 121/298 - (40%)
• Gaps: 63/298 - (21%)

  Fly    13 PHPHSYGGPHPHHSVPHGPLPP---------GMPMPSLGPFGLPHGLEAVGF-SQGMWGVN---- 63
            |.||.. ||..|.:.|..|..|         ...:|.....|.|.|.|..|. ..|..|.:
Human    56 PPPHDM-GPAFHLARPADPREPLENSASESSDTELPEKERGGEPKGPEDSGAGGTGCGGADDPAK 119

  Fly    64 TRKQRRERTTFTRAQLDVLEALFGKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQLQQ 128
            .:||||:||.||..||..|||.|.:.||||:.||||:|:..||.|.||:|||||||||.|::.:.
Human   120 KKKQRRQRTHFTSQQLQELEATFQRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRAKWRKRERN 184

  Fly   129 QQQSNSLSSSKNA----------------SGGGSGNSCSSSSANSRSNSNNNGSSSNNNTQSSGG 177
            ||    |...|..                :.|.|.|:.::.|......|..:.:..|:.:..|..
Human   185 QQ----LDLCKGGYVPQFSGLVQPYEDVYAAGYSYNNWAAKSLAPAPLSTKSFTFFNSMSPLSSQ 245

  Fly   178 NNSNKSSQKQGNSQSSQQGGG------SSGGNNSNNNSAAAAASAA------------------- 217
            :..:..|.....:..|..|.|      :||.||.||.:.::..||.
Human   246 SMFSAPSSISSMTMPSSMGPGAVPGMPNSGLNNINNLTGSSLNSAMSPGACPYGTPASPYSVYRD 310

  Fly   218 ---AAVAAAQSIKTHHSSFLSAAAAAASGGTNQSANNN 252
               :::|:.:.....||||........:.|.|....|:
Human   311 TCNSSLASLRLKSKQHSSFGYGGLQGPASGLNACQYNS 348

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
oc	NP_001356934.1	Homeodomain	68..123	CDD:459649	35/54 (65%)
PITX1	XP_047273274.1	Homeodomain	124..180	CDD:459649	35/55 (64%)
		OAR	310..327	CDD:461067	1/16 (6%)