Protein Alignment oc and OTX1

DIOPT Version :9

• Sequence 1: NP_001356934.1
• Gene: oc / 31802
• FlyBaseID: FBgn0004102
• Length: 664
• Species: Drosophila melanogaster
• Sequence 2: NP_001186699.1
• Gene: OTX1 / 5013
• HGNCID: 8521
• Length: 354
• Species: Homo sapiens
• Alignment Length: 501
• Identity: 146/501 - (29%)
• Similarity: 194/501 - (38%)
• Gaps: 173/501 - (34%)

  Fly    47 PHGLEAVGF----------SQGMWGVNTRKQRRERTTFTRAQLDVLEALFGKTRYPDIFMREEVA 101
            |:|:..:|.          |.| :....||||||||||||:|||||||||.||||||||||||||
Human     9 PYGMNGLGLAGPAMDLLHPSVG-YPATPRKQRRERTTFTRSQLDVLEALFAKTRYPDIFMREEVA 72

  Fly   102 LKINLPESRVQVWFKNRRAKCRQQLQQQQQSNSLSSSKNASGGGSGNSCSSSSANSRSNSNNNGS 166
            ||||||||||||||||||||||    |||||.|.:.|:.|..       .||.....|.|.::|.
Human    73 LKINLPESRVQVWFKNRRAKCR----QQQQSGSGTKSRPAKK-------KSSPVRESSGSESSGQ 126

  Fly   167 SSNNNTQSSGGNNSNKSSQKQGNSQSSQQGGGSSGGNNSNNNSAAAAASAAAAVAAAQSIKTHHS 231
            .:.....||..::|:.||                  :::|..:||||......||||.|:.|..:
Human   127 FTPPAVSSSASSSSSASS------------------SSANPAAAAAAGLGGNPVAAASSLSTPAA 173

  Fly   232 SFLSAAAAAASGGTNQSANNNSNNNNQGNSTPNSSSSGGGGGSQAGGHLSAAAAAAALNVTAAHQ 296
            |.:.:.|:.:.|                 |.|.|              :|.....||.:.|:..|
Human   174 SSIWSPASISPG-----------------SAPAS--------------VSVPEPLAAPSNTSCMQ 207

  Fly   297 NSSPLLPTPATSVSPVSIVCKKEHLSGGYGSSVGGGGGGGGASSGGLNLGVGVGVGVGVGVGVSQ 361
            .|.......|.:..|:|           ||.  ||..|.|..:......|         ||..|.
Human   208 RSVAAGAATAAASYPMS-----------YGQ--GGSYGQGYPTPSSSYFG---------GVDCSS 250

  Fly   362 DLLRSPYDQLKDAGGDIGAGVHHHHSIYGSAAGSNPRLLQPGGNITPMDSSSSITTPSPPITPMS 426
            .|                |.:|.||         :|..|                      :||:
Human   251 YL----------------APMHSHH---------HPHQL----------------------SPMA 268

  Fly   427 PQSAAAAAHAAQSAQSAHHSAAHSAAYMSNHDSYNFWHNQYQQYPNNYAQAPSYYSQMEYFSNQN 491
            |.|.|...|        ||..||.....|:...::..|:.:|.|..:...          |::.:
Human   269 PSSMAGHHH--------HHPHAHHPLSQSSGHHHHHHHHHHQGYGGSGLA----------FNSAD 315

  Fly   492 QVNYNMGHSGYTASNFGLSPSPSFTGTVSAQAFSQNSLDYMSPQDK 537
            .::|.               .|......||...:.||.|.:..:|:
Human   316 CLDYK---------------EPGAAAASSAWKLNFNSPDCLDYKDQ 346

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
oc	NP_001356934.1	Homeobox	71..123	CDD:333795	49/51 (96%)
OTX1	NP_001186699.1	Homeobox	42..95	CDD:395001	51/56 (91%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	91..146		22/83 (27%)
		TF_Otx	180..274	CDD:397546	35/193 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	257..305		17/86 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2251
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000011
OrthoInspector	1	1.000	-	-		otm41031
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR45793
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3028
SonicParanoid	1	1.000	-	-		X850
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	9	8.900