Protein Alignment oc and otx2b

DIOPT Version :10

• Sequence 1: NP_001356934.1
• Gene: oc / 31802
• FlyBaseID: FBgn0004102
• Length: 664
• Species: Drosophila melanogaster
• Sequence 2: NP_571326.1
• Gene: otx2b / 30501
• ZFINID: ZDB-GENE-980526-406
• Length: 289
• Species: Danio rerio
• Alignment Length: 308
• Identity: 106/308 - (34%)
• Similarity: 138/308 - (44%)
• Gaps: 81/308 - (26%)

  Fly    33 PP----GMPMPSLGPFGLPHGLEAVGFSQGMWGVNTRKQRRERTTFTRAQLDVLEALFGKTRYPD 93
            ||    |:.:.:.| ..|.|  .:||:.     ...||||||||||||||||||||||.||||||
Zfish     8 PPYTVNGLSLTTSG-MDLLH--PSVGYP-----ATPRKQRRERTTFTRAQLDVLEALFAKTRYPD 64

  Fly    94 IFMREEVALKINLPESRVQVWFKNRRAKCRQQLQQQQQSNSLSSSKNASGGGSGNSCSSSSANSR 158
            ||||||||||||||||||||||||||||||||.||||
Zfish    65 IFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQQQ---------------------------- 101

  Fly   159 SNSNNNGSSSNNNTQSSGGNNSNKSSQKQGNSQSSQQGGGSSGGNNSNNNSAAAAASAAAAVAAA 223
                            :||.|..:.::|:  |..:::....||.:......::.:..|.:...|.
Zfish   102 ----------------NGGQNKVRPAKKK--SSPAREASSESGASGQFTPPSSTSVPAISTTTAP 148

  Fly   224 QSIKTHHSSFLSAAAAAASGGTNQSANNNSNNNNQGNSTPNSSSSGGGGGSQAGGHLSAAAAAAA 288
            .||.:..|....:...:.|....|.:...:.....|.|...:.|:...||...|.:|
Zfish   149 VSIWSPASISPLSDPLSTSSSCMQRSYPMTYTQASGYSQGYAGSTSYFGGMDCGSYL-------- 205

  Fly   289 LNVTAAHQNSSPLLPTPATSVSPVSIVCKKEHL--------SGGYGSS 328
               |..|..    |..|.:::||:|......||        :.|||:|
Zfish   206 ---TPMHHQ----LTGPGSTLSPMSSNAVTSHLNQSPASLPTQGYGAS 246

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
oc	NP_001356934.1	Homeodomain	68..123	CDD:459649	53/54 (98%)
otx2b	NP_571326.1	Homeodomain	39..94	CDD:459649	53/54 (98%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	93..142		15/94 (16%)
		TF_Otx	153..234	CDD:427350	19/95 (20%)