DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment oc and VAX2

DIOPT Version :9

Sequence 1:	NP_001356934.1	Gene:	oc / 31802	FlyBaseID:	FBgn0004102	Length:	664	Species:	Drosophila melanogaster
Sequence 2:	NP_036608.1	Gene:	VAX2 / 25806	HGNCID:	12661	Length:	290	Species:	Homo sapiens

Alignment Length:	177	Identity:	53/177 - (29%)
Similarity:	74/177 - (41%)	Gaps:	45/177 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 AGFLKSGDLGPHPHSYGG---PHPHHSVPHGPLPPGMPMP----------------SLGPFGLPH 48
            ||.|::...|..|....|   ..|..|...|....|.|.|                ::....||.
Human    31 AGDLRADGGGHSPTEVAGTSASSPAGSRESGADSDGQPGPGEADHCRRILVRDAKGTIREIVLPK 95

  Fly    49 GLEAVGFSQGMWGVNTRKQRRERTTFTRAQLDVLEALFGKTRYPDIFMREEVALKINLPESRVQV 113
            ||:            ..:.:|.||:||..||..||..|.:.:|.....|.|:|.::||.|::|:|
Human    96 GLD------------LDRPKRTRTSFTAEQLYRLEMEFQRCQYVVGRERTELARQLNLSETQVKV 148

  Fly   114 WFKNRRAKCRQQLQQQQQSNSLSSSKNASGGGSGNSCSSSSANSRSN 160
            ||:|||.|     |::.||..|  .|.||.       |:|.|.:.||
Human   149 WFQNRRTK-----QKKDQSRDL--EKRASS-------SASEAFATSN 181

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
oc	NP_001356934.1	Homeobox	71..123	CDD:333795	24/51 (47%)
VAX2	NP_036608.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..75		12/43 (28%)
		Homeobox	105..158	CDD:306543	24/57 (42%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	205..240
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910