Protein Alignment oc and Shox2

DIOPT Version :10

• Sequence 1: NP_001356934.1
• Gene: oc / 31802
• FlyBaseID: FBgn0004102
• Length: 664
• Species: Drosophila melanogaster
• Sequence 2: NP_038693.1
• Gene: Shox2 / 20429
• MGIID: 1201673
• Length: 331
• Species: Mus musculus
• Alignment Length: 262
• Identity: 82/262 - (31%)
• Similarity: 112/262 - (42%)
• Gaps: 56/262 - (21%)

  Fly    19 GGPHPHHSVPHGPL----PPGMP-MPSLGPFGLPHGLEAVGFSQGMWGVNTRKQRRERTTFTRAQ 78
            ||..|...:..|..    .||.| :..:.|.......:|.|....  |....||||.||.||..|
Mouse    89 GGRSPVRELDMGAAERSREPGSPRLTEVSPELKDRKDDAKGMEDE--GQTKIKQRRSRTNFTLEQ 151

  Fly    79 LDVLEALFGKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQLQQQQQSNSLSSSKNASG 143
            |:.||.||.:|.|||.|||||::.::.|.|:||||||:|||||||:|..|..:...:.::
Mouse   152 LNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQLHKGVLIGAA----- 211

  Fly   144 GGSGNSCSSSSANSRSNSNNNGSSSNNNTQSSGGNNSNKSSQKQGNSQSSQQGGGSSGGNNSNNN 208
                   |...|...:...|.|:......|.|..|.:..|.|.|...|.      .|...:::::
Mouse   212 -------SQFEACRVAPYVNVGALRMPFQQDSHCNVTPLSFQVQAQLQL------DSAVAHAHHH 263

  Fly   209 -------------------------SAAAAASAAAAVAAAQSIKT--HHSSF----LSAAAAAAS 242
                                     .||.:||||:.||||.:.||  .:||.    |.|...||:
Mouse   264 LHPHLAAHAPYMMFPAPPFGLPLATLAADSASAASVVAAAAAAKTTSKNSSIADLRLKAKKHAAA 328

  Fly   243 GG 244
            .|
Mouse   329 LG 330

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
oc	NP_001356934.1	Homeodomain	68..123	CDD:459649	34/54 (63%)
Shox2	NP_038693.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..20
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	26..140		11/52 (21%)
		Homeodomain	141..197	CDD:459649	35/55 (64%)
		OAR	311..327	CDD:461067	4/15 (27%)
		OAR. /evidence=ECO:0000255|PROSITE-ProRule:PRU00138	313..326		4/12 (33%)