Protein Alignment oc and Phox2b

DIOPT Version :10

• Sequence 1: NP_001356934.1
• Gene: oc / 31802
• FlyBaseID: FBgn0004102
• Length: 664
• Species: Drosophila melanogaster
• Sequence 2: NP_032914.1
• Gene: Phox2b / 18935
• MGIID: 1100882
• Length: 314
• Species: Mus musculus
• Alignment Length: 324
• Identity: 106/324 - (32%)
• Similarity: 137/324 - (42%)
• Gaps: 97/324 - (29%)

  Fly    11 LGPHPHSYGGPHPHHSVPHGPLPPGMPMPSLGPFGL--PHGLEAVGFSQGMWGVN-TRKQRRERT 72
            |.|...|.|....|.|.|:..:          |:.|  .||           |:| .|||||.||
Mouse    60 LTPGSCSLGTLRDHQSSPYAAV----------PYKLFTDHG-----------GLNEKRKQRRIRT 103

  Fly    73 TFTRAQLDVLEALFGKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQLQQQQQSNSLSS 137
            |||.|||..||.:|.:|.||||:.|||:||||:|.|:||||||:|||||.|:  |::..:.:.::
Mouse   104 TFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAKFRK--QERAAAAAAAA 166

  Fly   138 SKNASGGGSGNSC---SSSSANSRSNSNNNGSSSN-NNTQSSGGNNSNKSSQKQGNSQSSQQGGG 198
            :||.|.|...:|.   .|..|.|....:..|...| |.|.|.|.|.....    |.|.:...|..
Mouse   167 AKNGSSGKKSDSSRDDESKEAKSTDPDSTGGPGPNPNPTPSCGANGGGGG----GPSPAGAPGAA 227

  Fly   199 SSGGNNSNNNSAAAAASAAAAVAAAQSIKTHHSSFLSAAAAAASGGTNQSANNNSNNNNQGNSTP 263
            ..||.........|||:||||.|||           :||||||:||.
Mouse   228 GPGGPGGEPGKGGAAAAAAAAAAAA-----------AAAAAAAAGGL------------------ 263

  Fly   264 NSSSSGGGGGSQAGGHLSAAAAAAALNVTAAHQNSSPLLPTPATSVSPVSIVCKKEHLSGGYGS 327
              :::||.|...|.|                        |.|.||:        .:.|.|.:.|
Mouse   264 --AAAGGPGQGWAPG------------------------PGPITSI--------PDSLGGPFAS 293

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
oc	NP_001356934.1	Homeodomain	68..123	CDD:459649	38/54 (70%)
Phox2b	NP_032914.1	Homeodomain	99..155	CDD:459649	38/55 (69%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	162..246		23/87 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	259..289		13/81 (16%)