Protein Alignment oc and Pitx2

DIOPT Version :10

• Sequence 1: NP_001356934.1
• Gene: oc / 31802
• FlyBaseID: FBgn0004102
• Length: 664
• Species: Drosophila melanogaster
• Sequence 2: NP_001035967.1
• Gene: Pitx2 / 18741
• MGIID: 109340
• Length: 324
• Species: Mus musculus
• Alignment Length: 367
• Identity: 101/367 - (27%)
• Similarity: 131/367 - (35%)
• Gaps: 116/367 - (31%)

  Fly     2 AAGFLKSGDLGPHPHSYGGPHPHHSVPHGPLPPGMPMPSLGPFGLPHGLEAVGFS---------- 56
            |||...|....|..|     ||........|.||.|. ||.  ...|.||....|
Mouse    14 AAGTKLSAASSPFCH-----HPQALAMASVLAPGQPR-SLD--SSKHRLEVHTISDTSSPEVAEK 70

  Fly    57 -QGMWGVN----------TRKQRRERTTFTRAQLDVLEALFGKTRYPDIFMREEVALKINLPESR 110
             :|..|.|          .::|||:||.||..||..|||.|.:.||||:..|||:|:..||.|:|
Mouse    71 DKGQQGKNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEAR 135

  Fly   111 VQVWFKNRRAKCRQQLQQQQQSNSLSSSKNASGGGSGNSCSSSSANSRSNSNNNGSSSNNNTQSS 175
            |:|||||||||.|::.:.||    ....||..|                 ...||.....:....
Mouse   136 VRVWFKNRRAKWRKRERNQQ----AELCKNGFG-----------------PQFNGLMQPYDDMYP 179

  Fly   176 GGNNSNKSSQKQGNSQSSQQGGGSSGGNNSNNNSAAAAASAAAAVAAAQSIKTHHSSFLSAAAAA 240
            |                           .|.||.||...::|       |:.|....|.:
Mouse   180 G---------------------------YSYNNWAAKGLTSA-------SLSTKSFPFFN----- 205

  Fly   241 ASGGTNQSANNNSNNNNQGNSTPNSSSSGGGGGSQAGGHLSAAAAAAALNVTAAHQNSSPLL--- 302
                   |.|.|..::....|.|||.||.....|.....::....::..::...:..|||.|
Mouse   206 -------SMNVNPLSSQSMFSPPNSISSMSMSSSMVPSAVTGVPGSSLNSLNNLNNLSSPSLNSA 263

  Fly   303 -PTPATSVSP---------------VSIVCK-KEHLSGGYGS 327
             ||||...:|               .|:..| |:|.|.||.|
Mouse   264 VPTPACPYAPPTPPYVYRDTCNSSLASLRLKAKQHSSFGYAS 305

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
oc	NP_001356934.1	Homeodomain	68..123	CDD:459649	34/54 (63%)
Pitx2	NP_001035967.1	Homeodomain	93..149	CDD:459649	34/55 (62%)
		OAR	282..299	CDD:461067	3/16 (19%)