Protein Alignment oc and Otx2

DIOPT Version :10

• Sequence 1: NP_001356934.1
• Gene: oc / 31802
• FlyBaseID: FBgn0004102
• Length: 664
• Species: Drosophila melanogaster
• Sequence 2: NP_001273410.1
• Gene: Otx2 / 18424
• MGIID: 97451
• Length: 297
• Species: Mus musculus
• Alignment Length: 322
• Identity: 115/322 - (35%)
• Similarity: 145/322 - (45%)
• Gaps: 80/322 - (24%)

  Fly    33 PP----GMPMPSLGPFGLPHGLEAVGFSQGMW----GVNTRKQRRERTTFTRAQLDVLEALFGKT 89
            ||    |:.:.:.| ..|.|  .:||: .|.|    ....||||||||||||||||||||||.||
Mouse     8 PPYAVNGLSLTTSG-MDLLH--PSVGY-PGPWASCPAATPRKQRRERTTFTRAQLDVLEALFAKT 68

  Fly    90 RYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQLQQQQQSNSLSSSKNASGGGSGNSCSSSS 154
            ||||||||||||||||||||||||||||||||||||.||||
Mouse    69 RYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQQQ------------------------ 109

  Fly   155 ANSRSNSNNNGSSSNNNTQSSGGNNSNKSSQKQGN--SQSSQQGGGSSGGNNSNNNSAAAAASAA 217
                                :||.|..:.::|:.:  .:.|.:.|.|...:..::.|....||::
Mouse   110 --------------------NGGQNKVRPAKKKSSPAREVSSESGTSGQFSPPSSTSVPTIASSS 154

  Fly   218 AAVAAAQSIKTHHSSFLSAAAAAASGGTNQSANNNSNNNNQGNSTPNSSSSGGGGGSQAGGHLSA 282
            |.|    ||.:..|....:...:.|....|.:...:.....|.|...:.|:...||...|.:|
Mouse   155 APV----SIWSPASISPLSDPLSTSSSCMQRSYPMTYTQASGYSQGYAGSTSYFGGMDCGSYL-- 213

  Fly   283 AAAAAALNVTAAHQNSSPLLPTPATSVSPVSIVCKKEHLSGGYGSSVGGGGGGGGASSGGLN 344
                     |..|..    ||.|..::||:.......||:   .|.......|.||||.|.|
Mouse   214 ---------TPMHHQ----LPGPGATLSPMGTNAVTSHLN---QSPASLSTQGYGASSLGFN 259

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
oc	NP_001356934.1	Homeodomain	68..123	CDD:459649	53/54 (98%)
Otx2	NP_001273410.1	Homeodomain	47..102	CDD:459649	53/54 (98%)
		TF_Otx	161..242	CDD:427350	19/98 (19%)