Protein Alignment oc and Phox2a

DIOPT Version :10

• Sequence 1: NP_001356934.1
• Gene: oc / 31802
• FlyBaseID: FBgn0004102
• Length: 664
• Species: Drosophila melanogaster
• Sequence 2: NP_032913.1
• Gene: Phox2a / 11859
• MGIID: 106633
• Length: 280
• Species: Mus musculus
• Alignment Length: 378
• Identity: 94/378 - (24%)
• Similarity: 119/378 - (31%)
• Gaps: 170/378 - (44%)

  Fly    29 HGPLPP-----GMPMPSLGP-----------------------FGLPHGLEAVGFSQGMWGVNTR 65
            :.||.|     |.|.|:||.                       |..|.||.           ..|
Mouse    35 YSPLRPAFPAAGPPCPALGSSNCALGALRDHQPAPYSAVPYKFFPEPSGLH-----------EKR 88

  Fly    66 KQRRERTTFTRAQLDVLEALFGKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQLQQQQ 130
            ||||.|||||.|||..||.:|.:|.||||:.|||:||||:|.|:||||||:|||||.|:|
Mouse    89 KQRRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAKFRKQ----- 148

  Fly   131 QSNSLSSSKNASGGGSGNSCSSSSANSRSNSNNNGSSSNNNTQSSGGNNSNKSSQKQGNSQSSQQ 195
                                                                             
Mouse   149 ----------------------------------------------------------------- 148

  Fly   196 GGGSSGGNNSNNNSAAAAASAAAAVAAAQSIKTHHSSFLSAAAAAASGGTNQSANNNSNNNNQGN 260
                         ..||:|..||                 .|..|..|....|:.::.:..:..:
Mouse   149 -------------ERAASAKGAA-----------------GATGAKKGEARCSSEDDDSKESTCS 183

  Fly   261 STPNSSSSGGGGGSQAGGHLSAAAAAAALNVTAAHQNSSPLLPTPATSVSPVSIVCKK----EHL 321
            .||:|::|           |....|              |.|.:|..|.||:......    :.|
Mouse   184 PTPDSTAS-----------LPPPPA--------------PSLASPRLSPSPLPAALGSGPGPQPL 223

  Fly   322 SGGYGSSVGGGGGGGGASSGG--LNLGVGVGVGVGVGVGVSQDLLRSPYDQLK 372
            .|...:.|.||||||..:...  |........|.|...||.....|.|...||
Mouse   224 KGALWAGVAGGGGGGPGTGAAELLKAWQPAEPGPGPFSGVLSSFHRKPGPALK 276

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
oc	NP_001356934.1	Homeodomain	68..123	CDD:459649	38/54 (70%)
Phox2a	NP_032913.1	Homeodomain	91..147	CDD:459649	38/55 (69%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	145..244		32/223 (14%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	260..280		6/17 (35%)