DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment oc and VAX1

DIOPT Version :9

Sequence 1:	NP_001356934.1	Gene:	oc / 31802	FlyBaseID:	FBgn0004102	Length:	664	Species:	Drosophila melanogaster
Sequence 2:	NP_001106175.1	Gene:	VAX1 / 11023	HGNCID:	12660	Length:	334	Species:	Homo sapiens

Alignment Length:	291	Identity:	78/291 - (26%)
Similarity:	112/291 - (38%)	Gaps:	94/291 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    61 GVNTRKQRRERTTFTRAQLDVLEALFGKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQ 125
            |::..:.:|.||:||..||..||..|.:.:|.....|.|:|.::||.|::|:|||:|||.|   |
Human    94 GLDLDRPKRTRTSFTAEQLYRLEMEFQRCQYVVGRERTELARQLNLSETQVKVWFQNRRTK---Q 155

  Fly   126 LQQQQQSNSLSS--SKNASGGGSGNSCSSSSANSRSNSNNNGSSSNNNTQSSGGNNSNKSSQKQG 188
            .:.|.:.:.|.|  |:.|:      :||....                             .:||
Human   156 KKDQGKDSELRSVVSETAA------TCSVLRL-----------------------------LEQG 185

  Fly   189 NSQS-------------SQQGGGSSGGNNSNNNSAAAAASAAAAVAAAQSIKTHHSSFLSAAAAA 240
            ...|             ...|....|.:.....:.|||.|||||.|||..         .|.||:
Human   186 RLLSPPGLPALLPPCATGALGSALRGPSLPALGAGAAAGSAAAAAAAAPG---------PAGAAS 241

  Fly   241 ----ASGGTNQSANNNSNNNNQGNSTPNSSSSGGGG---GSQAGGH-LSAAAAAAALNVTAAHQN 297
                |.||                 .|....:|.||   |:.|.|| |.:....:.|...|:..:
Human   242 PHPPAVGG-----------------APGPGPAGPGGLHAGAPAAGHSLFSLPVPSLLGSVASRLS 289

  Fly   298 SSPLLPTPATSVSPVSIVCKKEHLSGGYGSS 328
            |:||  |.|.|::.     ..:.||..|.||
Human   290 SAPL--TMAGSLAG-----NLQELSARYLSS 313

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
oc	NP_001356934.1	Homeobox	71..123	CDD:333795	24/51 (47%)
VAX1	NP_001106175.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..41
		COG5576	66..184	CDD:227863	34/127 (27%)
		Homeobox	103..157	CDD:365835	25/56 (45%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	234..263		10/54 (19%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	314..334		78/291 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	83	1.000	Inparanoid score	I5194
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.960