Protein Alignment Caf1-180 and Caf1-180

DIOPT Version :10

• Sequence 1: NP_572495.1
• Gene: Caf1-180 / 31801
• FlyBaseID: FBgn0030054
• Length: 1183
• Species: Drosophila melanogaster
• Sequence 2: XP_061499498.1
• Gene: Caf1-180 / 1282061
• VectorBaseID: AGAMI1_005692
• Length: 1095
• Species: Anopheles gambiae
• Alignment Length: 1318
• Identity: 392/1318 - (29%)
• Similarity: 571/1318 - (43%)
• Gaps: 388/1318 - (29%)

  Fly    22 KSAEKTASG--GKKFVQTRLPFKLLTPGGGAVPTSSSSSSSPATIGSGPVTVILDEDDPA-PRKR 83
            :.:.|.:.|  .:|..|:||||::|             |:|..|.           |:|. .|||
Mosquito    10 QDSSKLSPGASARKMKQSRLPFQIL-------------STSAKTF-----------DEPVEARKR 50

  Fly    84 KLSYDDESPSEGTGCSTGQL----RRSTSKENLDLASSIATKKVKTTDSVVEDVIELDE-DEADK 143
            |.|.:        |...|.:    |.|..|||:....:..|:|         .::|:.| :..:.
Mosquito    51 KPSTE--------GIDLGHVAKAGRISEVKENVTTLVAEETRK---------QIVEIAEPNVTNA 98

  Fly   144 EIEDQDQLVEAK---SSKEVKLKPKKSEGKKGSPAPIQIKLPLVNKRSKRRKSLKKSEEPLETST 205
            ::|..:..|...   :||..|....||:.|:.....|.||||:    .||::.|.|
Mosquito    99 DMETSEPAVGCSGLPTSKANKKSSGKSDVKRTESPKILIKLPI----GKRKRPLGK--------- 150

  Fly   206 ADVAKGDSESSDDIEIIAEELNPQKRQKVQTPREKSPENSSTSGKHTEEVMQKN----GKDSKKQ 266
                                :.|.||:.....|      .:.||..|.||:..:    ..||..:
Mosquito   151 --------------------VKPVKRKAFIEDR------LNLSGGITNEVLILDDTDLSDDSIDE 189

  Fly   267 EESMKAVKESKKEEPKTAEQNKKN----DQATIDLFMGKKMETNKKDKPEVKTTAKDNK--KDPL 325
            .|:.|::  |.||:.|....|.||    ..:||.|                :::|||.|  .|.:
Mosquito   190 TENWKSL--SVKEDSKILHDNSKNVTMTPNSTIVL----------------ESSAKDYKFVADSV 236

  Fly   326 IAEDSKPKEVPKKETSKTGGKGKKEGAKPAEKSKKEEKEDSTTKSKKEKADSPANNQKEQQIGVK 390
            ...|:|...:...:.                        |:..|             |||.:...
Mosquito   237 GVSDTKTNYIGSPQL------------------------DAIVK-------------KEQDMEAL 264

  Fly   391 KKTSEPEDASNSHKSVTAKKDSKKDEASTQVKSDNESPEAAEISMILSTSEANSSSSEHEMD-AD 454
            .|    ||....|..|..|..||.|.:|:                      ||.....:::| ::
Mosquito   265 FK----EDIFAPHTEVELKTHSKTDRSSS----------------------ANFVDPSYDIDSSE 303

  Fly   455 TDTAATDRPSAQKETRLNRKSLP-EVTGAPKGLTPKQ-QRLMEQRK------KAREEKEQKLAEE 511
            .|......|        |.|.:| |.....:.||||| .|..|..|      |.:|||.:||.:|
Mosquito   304 DDVYMLCTP--------NSKIVPNEDDNRARKLTPKQIARRQEYEKRQAIKQKEKEEKLRKLQQE 360

  Fly   512 R-----------RLKQQDKEHREQQKKQERDEK-----------EQQRKLERDQKEQQRKMEKEE 554
            :           ||:::::|.:|:||::||:||           |:|::.||::||:.::.|:||
Mosquito   361 KDEKAREKEEQERLRRKEREEKEEQKRKEREEKEELRRRDREEREEQKRKEREEKEEHKRKEREE 425

  Fly   555 KERKRQAEVDSKNEEKRKRNEAKEEVQRKKDEERRKKEQEREEAEQKKKRAAESFSKFFVPKQPK 619
            ||||||.|::.||||:|.:.|.:.:.:.:|:|||::||:|:|..|::|::.|::|:.||| |:|.
Mosquito   426 KERKRQVEIEQKNEERRLKEEERRKKEEQKEEERKRKEEEKEAEEKRKQKVAQAFTSFFV-KKPI 489

  Fly   620 CGSGSNNTSYLEHEQSSCDSSKASSQTL-----AFRPFQIKDDMLLAPIVRNSLGQEQRSQLDGL 679
            .|.|. ..|..|:...||.....|:.|.     .|.||.:|.||.|||.||..|...||..|:.:
Mosquito   490 NGGGV-KASDDENSVESCFGGITSTTTTIMERQRFMPFCVKGDMRLAPTVRRVLDDVQRDALERV 553

  Fly   680 FRHRDE-EADDEEEEEEQDIVRRKPPNRANLYLSELSSGRRKPLKMQRDVKLQRRTKDEEDDDDV 743
            |...|: :|.|                |.||||.:|.|...||||..|...::    |||:.||:
Mosquito   554 FYITDDGQAMD----------------RTNLYLEKLKSKSHKPLKTDRTWNVE----DEEECDDI 598

  Fly   744 QVIDYLSPAGLPIEVEQPKQLTRMKAKYLHFADNRRPPYYGTWRKKSSSISARRPLAQDKVLFDY 808
            .|:|  ......||.:..|...::|.|:..|.:||||||.|||||:|..|.||||.|||...|||
Mosquito   599 MVVD--ENVCHQIEEDPGKMKQKLKTKFFLFEENRRPPYRGTWRKRSCLIKARRPFAQDMKFFDY 661

  Fly   809 EVDSDCEWEEEEPGESLSASEDEKEKESEEESEEEYNEWYVPHGHLSDEELQNDGDGMEDGHTRE 873
            |||||.|||||||||||..|:|||:.:.||:.|.: ||::|||||||||||..:.:|..|.::.|
Mosquito   662 EVDSDDEWEEEEPGESLHGSDDEKDVDPEEDYEVD-NEFFVPHGHLSDEELHAEEEGEIDDNSPE 725

  Fly   874 AQKAKLQVLQQEFAQEMKKQTKKIKARLLGPVWLD---ENGNKSELFPAIFAHTIDMYACWQVEP 935
            .||.||:::||||..||||:|:|||.||:|.:|.:   |:..:|....||....:|       :.
Mosquito   726 VQKVKLKLMQQEFVAEMKKKTEKIKPRLIGCIWTNVSAEDKARSSECSAIIWKMLD-------DR 783

  Fly   936 LSLEPPPEP--------------ERQDQTPEQP---------VPLQLDDRLMQQLVRLTHGNRNS 977
            ..|..|.||              ..||.|...|         ..:::.|..:..|.||.|||.|:
Mosquito   784 AMLYNPDEPISFTRSHSRANGSCNDQDLTSISPSKDIEKSVIKKVKITDEAVCDLARLVHGNVNN 848

  Fly   978 KTFLINEYLEYLKTQATAEANQTTLPSKAVLREKFDELASWKTVELSTPEAAAASANSAKKGRKP 1042
            :.||:.|:..:..::     |::...|...:|.|..|:|.|          .|.......:|
Mosquito   849 RKFLVREFHAFWNSR-----NESVEFSFESIRNKIKEIAKW----------GACRIKGTMEG--- 895

  Fly  1043 KKRLCWVVASDMLEKFQLPDLQLQNQWNYTLTP----KVSDGPDAAQQ-----EQSPPADAVPAA 1098
              :|||.|.:.:||:.:|.||.|.|.|.|.|..    |:...|||.|:     :::||.|...|.
Mosquito   896 --KLCWTVENSVLEQCKLMDLPLPNDWKYQLQKESFIKMDKKPDAKQESKLETQKTPPIDTNNAR 958

  Fly  1099 SPAS-----------NQTTNSA------------------------------------------- 1109
            ..|:           |:||:.|
Mosquito   959 KDANEVTVSTSKTKLNETTSMAGSIVKFAKVMFKEDENETLVLDSSTLKKGLSSSLLKNLDSKKE 1023

  Fly  1110 -----PTTPISG-QTQAGQGVKKRATLIMSVPRDQPIPSATKNKLISQFL---QRQSDASKPKEK 1165
                 |.|..|. :|...|..|||..|:|||||.|.|..:|||.||||||   .|::|.|..|.
Mosquito  1024 KNTTKPATKCSSTETFTDQNSKKRVKLLMSVPRGQNINQSTKNNLISQFLCRENRKNDQSIKKS- 1087

  Fly  1166 MQEKPPPIVFDDVVMLSD 1183
                      ||.::..|
Mosquito  1088 ----------DDTIIEID 1095

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Caf1-180	NP_572495.1	PTZ00121	<131..603	CDD:173412	129/516 (25%)
		CAF1A	770..>813	CDD:463507	28/42 (67%)
		CAF1-p150_C2	947..>1127	CDD:434777	58/257 (23%)
Caf1-180	XP_061499498.1	None