DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sphinx1 and spirit

DIOPT Version :9

Sequence 1:	NP_729255.2	Gene:	sphinx1 / 318005	FlyBaseID:	FBgn0052383	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	NP_001162707.1	Gene:	spirit / 31797	FlyBaseID:	FBgn0030051	Length:	393	Species:	Drosophila melanogaster

Alignment Length:	303	Identity:	59/303 - (19%)
Similarity:	106/303 - (34%)	Gaps:	97/303 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 VVTLLVLSLTVSVGEKNKLSP---------RIAGGY--RAKTFTIIYLVG-------IVYFKSQT 50
            |..::..|...:..|.||:|.         .:.||.  |.:.|..:..:|       .:|::.
  Fly   101 VAPIVTRSSQQACNELNKVSKVKEIDEFFVSVVGGMPTRPREFPFMAALGWRSNFDQRIYYRC-- 163

  Fly    51 SSLNYGAGTIISNQWILTVKTVLKYSYIEVHLASRRSYRGFDI-------IRIYKENFR------ 102
                  .|.:|:|.::||.          .|.|        |:       :|:..:|..
  Fly   164 ------GGALIANNFVLTA----------AHCA--------DLGGEPPSQVRLGGDNLTLTEGED 204

  Fly   103 -------FHYD-------NDHVIALVKC-----PYQKFDRRMDRVRVPAYDTRFERYVGNMTMVC 148
                   .|.|       ||  |||::.     |..|          |......:.....:....
  Fly   205 ISIRRVIIHPDYSASTAYND--IALLELETAAKPELK----------PTCIWTQKEVTNTLVTAI 257

  Fly   149 GYGTEKRHAKLPEWMRCIEVEVMNNTECAKYYTP------LKWYEMCTSGE--GFKGVCEGDIGG 205
            |||...........:..:.::.::|.||..:|..      :...:|| :|:  |.:..|:||.||
  Fly   258 GYGQTSFAGLSSAQLLKVPLKSVSNEECQHHYQKDQLAQGVLGTQMC-AGDITGERDTCQGDSGG 321

  Fly   206 AVVTMGPNPTFIGIIWLMPENCSIGYPSVHIRVSDHIKWIKRV 248
            .::.......::..|..:.:.|:.|.|||:.|||..:.||:.:
  Fly   322 PLLMQDGLLGYVVGITSLGQGCASGPPSVYTRVSSFVDWIEGI 364

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sphinx1	NP_729255.2	Tryp_SPc	25..245	CDD:214473	51/268 (19%)
sphinx1	NP_729255.2	Tryp_SPc	26..248	CDD:304450	53/270 (20%)
spirit	NP_001162707.1	CLIP	51..98	CDD:197829
		Tryp_SPc	132..364	CDD:238113	53/270 (20%)
		Tryp_SPc	132..361	CDD:214473	51/267 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437051
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030