Protein Alignment CG32376 and KLK2

DIOPT Version :10

• Sequence 1: NP_729271.1
• Gene: CG32376 / 318002
• FlyBaseID: FBgn0052376
• Length: 291
• Species: Drosophila melanogaster
• Sequence 2: NP_005542.1
• Gene: KLK2 / 3817
• HGNCID: 6363
• Length: 261
• Species: Homo sapiens
• Alignment Length: 243
• Identity: 74/243 - (30%)
• Similarity: 103/243 - (42%)
• Gaps: 26/243 - (10%)

  Fly    64 TRIVNGKRIPCTEAPFQGSLHYEGYFVCGCVIINKIWILTAHHCFFGPPEKYTVRVGSDQQRRGG 128
            :|||.|........|:|.:::..|:..||.|:::..|:|||.||.....:.:..|....:....|
Human    23 SRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEPEDTG 87

  Fly   129 QLRHVKKIVALAAYN-----------DYTMRHDLAMMKLKSPVYFGKCVR----PVKLPSTKTTK 178
            |...|........||           |....|||.:::|..|......|:    |.:.|:..||.
Human    88 QRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPTQEPALGTTC 152

  Fly   179 FPKKFVVSGWGITSANAQNVQRYLRRVQIDYIKRSKCQKMYKKAGLKIYKDMICAS--RTNKDSC 241
            :     .||||..........|.|:.|.:..:....|.:.|.:   |:.:.|:||.  ...||:|
Human   153 Y-----ASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSE---KVTEFMLCAGLWTGGKDTC 209

  Fly   242 SGDSGGPLTSRGVLYGIVSWG-IGCANKNYPGVYVNCKRYVPWIKKVI 288
            .|||||||...|||.||.||| ..||....|.||.....|..|||..|
Human   210 GGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTI 257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32376	NP_729271.1	Tryp_SPc	65..284	CDD:214473	70/236 (30%)
KLK2	NP_005542.1	Tryp_SPc	25..256	CDD:238113	72/238 (30%)