Protein Alignment CG32376 and KLK1

DIOPT Version :10

• Sequence 1: NP_729271.1
• Gene: CG32376 / 318002
• FlyBaseID: FBgn0052376
• Length: 291
• Species: Drosophila melanogaster
• Sequence 2: NP_002248.1
• Gene: KLK1 / 3816
• HGNCID: 6357
• Length: 262
• Species: Homo sapiens
• Alignment Length: 245
• Identity: 72/245 - (29%)
• Similarity: 111/245 - (45%)
• Gaps: 29/245 - (11%)

  Fly    64 TRIVNGKRIPCTEAPFQGSLHYEGYFVCGCVIINKIWILTAHHCFFGPPEKYTVRVGSD---QQR 125
            :|||.|........|:|.:|::...|.||.:::::.|:|||.||.   .:.|.:.:|..   ...
Human    23 SRIVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWVLTAAHCI---SDNYQLWLGRHNLFDDE 84

  Fly   126 RGGQLRHVKKIVALAAYN-------------DYTMRHDLAMMKLKSPV-YFGKCVRPVKLPSTKT 176
            ...|..||.:......:|             ||:  |||.:::|..|. .....|:.|:|| |:.
Human    85 NTAQFVHVSESFPHPGFNMSLLENHTRQADEDYS--HDLMLLRLTEPADTITDAVKVVELP-TEE 146

  Fly   177 TKFPKKFVVSGWGITSANAQNVQRYLRRVQIDYIKRSKCQKMYKKAGLKIYKDMICASRT--NKD 239
            .:.....:.||||.......:....|:.|.:..:...:|:|.:.:   |:...|:|....  .||
Human   147 PEVGSTCLASGWGSIEPENFSFPDDLQCVDLKILPNDECKKAHVQ---KVTDFMLCVGHLEGGKD 208

  Fly   240 SCSGDSGGPLTSRGVLYGIVSWG-IGCANKNYPGVYVNCKRYVPWIKKVI 288
            :|.|||||||...|||.|:.||| :.|...|.|.|.|....||.||:..|
Human   209 TCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNKPSVAVRVLSYVKWIEDTI 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32376	NP_729271.1	Tryp_SPc	65..284	CDD:214473	69/238 (29%)
KLK1	NP_002248.1	Tryp_SPc	25..257	CDD:238113	70/240 (29%)