Protein Alignment CG32373 and Ltbp1

DIOPT Version :10

• Sequence 1: NP_729293.1
• Gene: CG32373 / 318000
• FlyBaseID: FBgn0052373
• Length: 486
• Species: Drosophila melanogaster
• Sequence 2: NP_067598.2
• Gene: Ltbp1 / 59107
• RGDID: 68379
• Length: 1712
• Species: Rattus norvegicus
• Alignment Length: 441
• Identity: 102/441 - (23%)
• Similarity: 153/441 - (34%)
• Gaps: 164/441 - (37%)

  Fly    94 CSNGI--WLGLKPNCIKIGKGNTHSMKQKKMRCRIDNGGCAHICNRSTHKCECYEGYTLNSTDLR 156
            |:.|.  |.|   .|:.:.:     ..|.|: |  .||.|.::  ..::.|.|::||: .:.|.|
  Rat  1017 CTEGFRGWNG---QCLDVDE-----CLQPKV-C--TNGSCTNL--EGSYMCSCHKGYS-PTPDHR 1067

  Fly   157 SCNDIDECKESNGGCSQVCNNLPGEFICTCNSGFEIDESDEKTCLDIDECADPELSWDCTAG-CK 220
            .|.|||||::.|...:..|.|..|.|.|||..|:::..:.:: |.|||||....|   |:.| |:
  Rat  1068 HCQDIDECQQGNLCMNGQCKNTDGSFRCTCGQGYQLSAAKDQ-CEDIDECEHRHL---CSHGQCR 1128

  Fly   221 NLNGTYKCL--------------------------------PSLVGRVEPTDGDGF--------- 244
            |..|:::||                                .:..|..:.|..||.
  Rat  1129 NTEGSFQCLCNQGYRASVLGDHCEDINECLEDSSVCQGGDCINTAGSYDCTCPDGLQLNDNKGCQ 1193

  Fly   245 ------SPG---------------EIVCKSGFKLSDDGSECQDINECDLADIDSDSWRMTYRYCE 288
                  .||               ..||:.||.:|.||..|:||:||           :....|:
  Rat  1194 DINECAQPGLCGPHGECLNTQGSFHCVCEQGFSISADGRTCEDIDEC-----------VNNTVCD 1247

  Fly   289 HK--CENTVGSYICHCPQGYHLLDDQNSCILDGSKLPPSKDAPVSQEAPRKDI--CPLFKGPANG 349
            ..  |:||.||:.|.|.||:....|...|:                     |:  |.|..|.. |
  Rat  1248 SHGFCDNTAGSFRCLCYQGFQAPQDGQGCV---------------------DVNECELLSGVC-G 1290

  Fly   350 KASCDKYLQNGFNYTRCNITCNAGYIMQGSQFAVCGHTGLWSSP-EAKCVESLALSCPVLTPPRN 413
            :|.|:.                    ::||...||.......|| ..:|              |:
  Rat  1291 EAFCEN--------------------VEGSFLCVCADENQEYSPMTGQC--------------RS 1321

  Fly   414 GRFYPASCNNEPSKSLAIC------ELLCDRGYLPRMDTQLIC---AAPWG 455
            .....:..:.:|.:....|      ..|||....|.:..|..|   .|.||
  Rat  1322 RATEDSGVDRQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWG 1372

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32373	NP_729293.1	FXa_inhibition	124..158	CDD:464251	10/33 (30%)
		FXa_inhibition	164..200	CDD:464251	10/35 (29%)
		FXa_inhibition	287..315	CDD:464251	11/29 (38%)
		CCP	340..398	CDD:153056	12/58 (21%)
Ltbp1	NP_067598.2	EGF_CA	907..948	CDD:214542
		EGF_CA	949..989	CDD:214542
		EGF_CA	990..1023	CDD:238011	2/5 (40%)
		EGF_CA	1030..1070	CDD:214542	12/50 (24%)
		EGF_CA	1071..1102	CDD:214542	14/30 (47%)
		EGF_CA	1112..1152	CDD:214542	13/42 (31%)
		EGF_CA	1153..1183	CDD:429571	2/29 (7%)
		EGF_CA	1194..1235	CDD:214542	9/40 (23%)
		EGF_CA	1236..1277	CDD:214542	15/51 (29%)
		8-Cys3 region. /evidence=ECO:0000250|UniProtKB:Q14766	1335..1402		10/38 (26%)
		TB	1350..1392	CDD:459903	8/23 (35%)
		EGF_CA	1458..>1484	CDD:214542
		C-terminal domain. /evidence=ECO:0000250|UniProtKB:Q14766	1498..1712
		TB	1526..1568	CDD:459903
		EGF_CA	1653..>1687	CDD:214542
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	63..148
		TB	559..594	CDD:459903
		EGF_CA	618..>648	CDD:214542
		TB	680..721	CDD:459903
		PHA03247	<703..860	CDD:223021
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	752..803